An efficient synthetic route to prepare O -(2- -benzyl-3,4-di- -acetyl-?/?- l -fucopyranosyl)-trichloroacetimidate from -fucose was developed by introducing the thiophenyl group at anomeric center and benzylidene functional protect 3 4 positions. Although three approaches were considered, best result obtained when, after 2-hydroxyl benzylation, both protective groups simultaneously removed usin...

Monoand di-protic alkyl and aryl phosphates, phosphonates, and thio analogues were determined in spiked samples of bacterial growth medium and human urine using a new procedure wlth a detection llmit of less than 2 pmol each. The acids were fully protonated by passing the aqueous samples through BioRad AG 50W-X8 (H') resin and dried thoroughly before refluxing with 3-benzyl-1-p-tolyltriazene in...

Relative yields of C-6, C-8. and C-6 and C-8 substituted catechins obtained from the reaction of (+ )-catechin or 3' 4',57-tetra-O-methvl-( + )-catechin with pyridinium hydrobromide-perbromide, bromine. p-hydroxybenzyl al~oh~I, or o-hydroxybenZyI alcohol showed differing selectivities depending upon the electrophile used. Ratios of C-6 to C-8 substituted products were 1 : 1.2 for the reaction o...