The effects of the benzamide derivatives, (-)-sulpiride, sultopride and nemonapride, on spontaneous and electrically evoked dopamine (DA) release from striatal slices of rats were investigated. Nemonapride at concentrations of 100 nM or higher caused a dose-dependent increase in spontaneous DA release from the slices. (-)-Sulpiride and sultopride had little effect on spontaneous DA release. The...

1,3-Thiazolidin-4-one analogues are important because of its versatile biological actions. In the present study, benzohydrazide (1) on condensation with different aromatic aldehydes (2a-g) in presence of catalytic amount of concentrated hydrochloric acid in absolute ethanol yield N'-[(E)(substitutedphenyl)methylidene]benzohydrazide (3a-g), which on cyclisation with 2sulfanylpropanoic acid in dr...

In the title compound, [Fe(C(5)H(5))(C(18)H(14)NO)], the unsubstituted cyclo-penta-dienyl ring is disordered over two sets of sites with occupancy ratio of 0.55 (1):0.45 (1). One conformation has the rings eclipsed and the other staggered. An intra-molecular C-H⋯O hydrogen bond forms an S(6) ring motif. In the crystal, inter-molecular C-H⋯O and N-H⋯O hydrogen bonds lead to R(2) (1)(7) ring moti...

The conformation of the N-H bond in the structure of the title compound, C(15)H(15)NO, is anti to the ortho and meta-methyl substituents in the aniline benzene ring, in contrast to the syn conformation observed with respect to the ortho and meta-chloro substituents in N-(2,3-dichloro-phen-yl)benzamide. Furthermore, the conformations of N-H and C=O bonds in the amide group are anti to each other...