In the present study, simulation of a divided wall column (DWC) was carried out to study the product quality and energy efficiency as a function of reflux rate, liquid spilt and vapour split for the separation of C4-C6 normal paraffin ternary mixture. Rigorous simulation of the DWC was carried out using Multifrac model of Aspen Plus software. Box–Behnken design (BBD) was used for the optimizati...

In the present work, the optimization of different structural and process parameters of a divided wall column (DWC) for the energy efficiency has been presented. The optimal design and operation of divided wall distillation columns involve a number of variables and is a non-linear problem. Rigorous simulation of a DWC was carried out using Multifrac model of ASPEN Plus software. Box–Behnken des...

background: we evaluated the efficacy of a simple belly-board device (bbd) designed and made in our department for reduction of small bowel inside the post-operative pelvic radiotherapy fields of rectal carcinomas. methods: a very simple bbd was designed and manufactured in our department. it was made of acrylic glass, and was 128 cm long, 40 cm wide, and 9 cm high, with a 25x25 cm square openi...

MicroRNAs are endogenous, small non-coding RNAs that control gene expression by directing their target mRNAs for degradation and/or posttranscriptional repression. Abnormal expression of microRNAs is thought to contribute to the development and progression of cancer. A history of benign breast disease (BBD) is associated with increased risk of subsequent breast cancer. However, no large-scale s...

In many diverse ecosystems, ranging from natural surfaces in aquatic ecosystems to the mammalian gut and medical implants, bacterial populations and communities exist as biofilms. While the process of biofilm development has been well-studied for those produced by unicellular bacteria such Pseudomonas aeruginosa, little is known about biofilm development associated with filamentous microorganis...

BACKGROUND Risk assessment of a benign breast disease/lesion (BBD) for invasive breast cancer (IBC) is typically done through a longitudinal study. For an infrequently-reported BBD, the shortage of occurrence data alone is a limiting factor to conducting such a study. Here we present an approach based on co-occurrence analysis, to help address this issue. We focus on fibroadenomatoid change (FA...

Studies of adult diet and risk of breast cancer have yielded mainly null results, but this does not rule out a possible impact of adolescent diet. This study examined associations between components of adolescent diet and risk of proliferative benign breast disease (BBD), a marker for breast cancer. The study population consisted of 29494 women in the Nurses' Health Study II who completed a que...

Genesis of breast cancer is a multistage process involving accumulation of genetic alterations, but little is known about the implication of genetic alterations in benign breast disease (BBD) lesions. Among benign lesions of the breast, one of the most common is fibroadenoma. The relationship between fibroadenoma and breast cancer is not clear. Some epidemiological studies show an association w...

Vascular abnormalities, including altered angiogenesis, are major factors contributing to the morbidity and mortality of diabetes. We hypothesized that impaired angiogenesis in diabetes results from decreased tetrahydrobiopterin (BH4)-dependent synthesis of nitric oxide (NO) by endothelial cells (EC). To test this hypothesis, we utilized EC from spontaneously diabetic BB (BBd) and nondiabetes-p...

In this study, a Box Behnken Design (BBD) and a Binary Logistic Regression (BLR) were applied to study the effects of demographic characteristics on the risk of HIV in South Africa. The demographic characteristics studied for each pregnant mother attending an antenatal clinic in South Africa, were mother’s age, partner’s age (father’s age), mother’s level of education and parity. Using the 2007...