BACKGROUND This study is aimed at investigating the effects of procyanidin on cardiomyocyte apoptosis of myocardial ischemia/reperfusion (I/R) injury in rats. METHODS Sprague-Dawley rats were randomly assigned into four groups: control group (normal saline), ischemic group (normal saline), procyanidin low-dose group (procyanidin 50 mg/kg/day) and procyanidin high-dose group (procyanidin 100 m...

Ciliary neurotrophic factor (CNTF) is a cytokine that plays a neuroprotective role in relation to axotomized motoneurons. We determined the effect of daily subcutaneous doses of CNTF (1.2 microg/g for 5 days; N = 13) or PBS (N = 13) on the levels of mRNA for Bcl-2 and Bax, as well as the expression and inter-association of Bcl-2 and Bax proteins, and the survival of motoneurons in the spinal co...

The effects of aflatoxin B1 (AFB1) exposure and sodium selenite supplementation on cell apoptosis of jejunum in broilers were studied. A total of 240 one-day-old male AA broilers were randomly assigned four dietary treatments containing 0 mg/kg of AFB1 (control), 0.3 mg/kg AFB1 (AFB1), 0.4 mg/kg supplement Se (+ Se) and 0.3 mg/kg AFB1 + 0.4 mg/kg supplement Se (AFB1 + Se), respectively. Compare...

Background and aims: The aim of this study was to investigate the combined effect interval training resveratrol consumption on regulatory executive factors hepatocyte apoptosis in male rats with diabetes. Methods: Frothy-two Wistar were randomly divided into healthy control, diabetic, saline supplement, intermittent exercise, resveratrol+intermittent exercise groups. program consisted 8 weeks a...

introduction: ischemia leads to loss of neurons by apoptosis in specific brain regions, especially in the hippocampus. the purpose of this study was investigating the effects of exercise preconditioning on expression of bax, bcl-2, and caspase-3 proteins in hippocampal ca1 neurons after induction of cerebral ischemia. methods: male rats weighing 260-300 g were randomly allocated into three grou...

Objective: Diabetes is a metabolic disease which is linked to increased physical disabilities and muscle tissue damage. The aim of this study was to investigate the effect of interval and continued exercises with crocin on Bax/Bcl-2 ratio in diabetic obese rats. Materials and Methods: In this clinical trial study, 56 adult diabetic rats (high-fat diet and venous injection of streptozotocin) we...

Alternatif tıpta kemoterapi benzeri tedavi yöntemlerine ek olarak sıklıkla bitkisel kökenli doğal ilaçlar kullanılmaktadır. Panax ginseng bunlardan biridir ve sinir sistemi kaynaklı hastalıklarda tercih edilmektedir. Çalışmamızda amaç, sisplatinden önce kullanılan ginsengin YKG1 glioblastoma hücrelerinde hücre ölümü canlılığı bakımından değerlendirilmesidir. Ticari satın alınan hücreleri, % 5 C...

the study was conducted to evaluate the effect of thermal stress on expression profile of genes related to apoptosis in peripartum sahiwal cows. for this, twelve pregnant dry sahiwal cows were selected from livestock research centre at national dairy research institute, karnal. the cows were divided into two groups consisting of six sahiwal cows each. cows of group i calved during thermoneutral...