OBJECTIVE Interleukin-6 (IL-6), a member of the gp130 cytokine family, is considered to be an important modulator of function and growth in endocrine anterior pituitary cells. In pituitary adenomas, where IL-6 is often produced by the tumour cells, it is thought to be involved in pituitary adenoma pathophysiology via autocrine/paracrine mechanisms. METHODS We have studied in primary cell cult...

The current study reports the case of a 68-year-old male who presented with a 4-month history of a painless slow-growing mass in the left parotid region. Magnetic resonance imaging revealed two independent, round lesions in the superficial and deep lobes of the parotid gland on the left side, respectively. A total parotidectomy was performed and basal cell adenomas (BCAs) were identified by his...

background:non-melanoma skin cancer (nmsc), the most prevalent types being squamous cell carcinoma (scc) and basal cell carcinoma (bcc), is the most common type of malignancy in human beings. these neoplasms are more frequent in the elderly and fair skinned people and mainly occur on sun-exposed sites of the body. ultraviolet b (uvb) has a well-known effect in induction and promotion of growth ...

Canalicular adenomas are uncommon benign salivary gland neoplasms of the oral cavity. They are typically located on the upper lip, buccal mucosa and infrequently found on the palate and derived from minor salivary glands. Intra-mandibular localization of canalicular adenoma is extremely rare. Due to benign character of the tumour, canalicular adenomas rarely present with bone erosion. Histologi...

Basal cell adenocarcinoma (BCAC), the malignant counterpart of basal cell adenoma, is a rare salivary gland neoplasm, the most common site being parotid gland. It has been classified as a low-grade tumor with a favourable prognosis. Only a few cases have been reported to occur in submandibular gland. This report describes a case of right submandibular swelling which was diagnosed as a vascular ...

background and aim: basal cell carcinoma (bcc) is the most common skin neoplasm and the most common type of cancer. since the incidence of injury is taken into consideration in the pathologic diagnosis, the study of clinical and microscopic views of bcc is of particular importance. the present study aimed at determining the frequency of clinical and microscopic views of bcc in a 10-year period ...

Basal cell adenoma is a rare entity belonging to group of basaloid tumours.1 It appears as a mass of very slow, progressive growth1,2 whose most common location is the parotid gland, although it can develop in any salivary gland.2,3 Due to the difficulty in differentiating it from other basaloid tumour subtypes of malignant nature, it requires a wide surgical resection and close clinical monito...

Benign laryngotracheal tumours of the minor salivary glands are rare,1 so experience in their treatment and evolution is limited. Indeed, we did not find any evidence of previous publication of a case of monomorphic adenoma in a subglottic location (PubMed, keys words: subglottic/laryngotracheal adenoma; larynx salivary adenoma; monomorphic/basal cell adenoma. Period covered: 1979–2012. Updated...

background & objectives:  cd10 is a cell surface enzyme with metalloendopeptidase activity, also known as common acute lymphoblastic leukaemia antigen, which mainly serves as a marker for acute lymphoblastic leukemia (all). to date and to the best of our knowledge, only few comparative immunohistochemical studies have assessed cd10 expression in cutaneous epithelial neoplasms. our goal was ...