Acute flaccid paralysis (AFP), other than paralytic poliomyelitis, are usually due to demyelination like Guillian Barre syndrome (GBS), transverse myelitis and traumatic neuritis. Poliomyelitis like illness, Hopkins syndrome or Post Asthmatic Amotrophy, associated with bronchial asthma and hyperIgEemia has been reported in literature. We present a two and a half year old child who developed AFP...

Objective: To determine the frequency of axonal variants in our patients of Guillain-Barre Syndrome. Study Design: Descriptive study. Place and Duration: Department of Neurology, Military Hospital, Rawalpindi and Armed Forces Institute of Rehabilitation Medicine (AFIRM) from 01 Jan 2009 to 30 Jul 2010. Patients and Methods: Forty adult patients meeting the National Institute of Neurological Dis...

The syndrome of acute inflammatory idiopathic polyneuropathy is well known, the predominently motor type of which is recognised by the name of Guillain-Barre Syndrome (GBS), in which the maximum neurological deficit develops rapidly in days, plateaus for weeks and then subsides with the recovery occurring in weeks to months. Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) has e...

Worldwide concern over Zika virus causing Guillain-Barre syndrome (GBS) soared after recent reports that Zika-related weakness was due to GBS. A global strategic response plan was initiated with recommendations for at-risk countries to prepare for GBS. This plan has major economic implications, as nations with limited resources struggle to implement costly immunotherapy. Since confirmation of c...

Background: Guillain-Barré syndrome (GBS) is an acute onset immune-mediated disease affecting the peripheral nerve also its root Plasma exchange(PE) and intravenous immuno globulin(IVIG) have given evidence for faster recovery in GBS(4). IVIG treatment comparatively costly but hospital stay duration reduced.Other options include corticosteroids not shown benefit. Mortality of GBS around 3%. Aro...

Molecular mimicry of Campylobacter jejuni lipo-oligosaccharides (LOS) with gangliosides in nervous tissue is considered to induce cross-reactive antibodies that lead to Guillain-Barre syndrome (GBS), an acute polyneuropathy. To determine whether specific bacterial genes are crucial for the biosynthesis of ganglioside-like structures and the induction of anti-ganglioside antibodies, we character...

The Guillain Barre Syndrome (GBS) is an acute immune mediated progressive polyneuropathy having monophasic illness leading to paralysis. clinical features are ascending symmetrical muscle weakness that may lead respiratory failure. Diagnosis based upon presentation and supported by a lumbar puncture with CSF analysis demonstrating albumin cytological dissociation electrophysiological studies. O...

Guillain-Barre syndrome (GBS) is a common cause of acute peripheral neuropathy and is characterized by hyporeflexia or areflexia. Hyperreflexia has been rarely reported with acute motor axonal neuropathy. A 10-year-old boy presented with asymmetrical weakness of upper and lower limbs and change of voice. Weakness progressed in the hospital with involvement of multiple cranial nerves, preserved ...

Guillain Barre Syndrome (GBS) is an inflammatory polyneuropathy characterized by acute onset, rapid progressive, ascending symmetric muscular weakness, pain, and paresthesia. The progressive phase peaks in 7 to 14 days and can lead to various levels of weakness, from abnormal gait to total paralysis, cranial nerve weakness, pain, respiratory compromise, and autonomic instability [1]. The autono...

Guillain-Barre syndrome (GBS)-associated achalasia is a very rare disease of uncertain cause. We report the case of a patient diagnosed with GBS-associated type I achalasia who was successfully treated with peroral endoscopic myotomy (POEM). A 30-year-old man who was diagnosed with GBS 3 mo before was referred to our department with dysphagia and meal-related regurgitation. The results of esoph...