Antilymphocyte therapies are widely used for immunosuppression in solid organ transplantation. These agents have varied mechanisms of action, with resulting differences in the intensity and duration of immunosuppression and in associated infectious complications. Induction therapy with antithymocyte globulins is associated with a greater incidence of cytomegalovirus, Epstein-Barr virus, and BK ...

Cerebrospinal fluid specimens from 226 patients with suspected viral infections of the central nervous system (CNS) were tested by polymerase chain reaction (PCR) to identify the most frequent viruses involved in these infections. A positive PCR result was obtained in 18 patients (7 cases positive for herpes simplex viruses, 5 for enterovirus, 3 for JC virus, 2 for varicella-zoster virus, and 1...

Cytomegalovirus (CMV), a member of the herpes family which includes herpes simplex virus (HSV) 1 and 2, varicella zoster virus (VZV), and Epstein-Barr virus (EBV), is ubiquitous worldwide. About 85% of persons above the age of 40 in the general community are seropositive.1 CMV infections manifest more usually in immunocompromised individuals especially in patients with acquired immune deficienc...

epstein barr virus (ebv) is one of seven known herpes virus pathogenic for humans.since it is ubiquitous, it infects nearly 95% of individuals worldwide by adulthood .ebv is the etiologic agent of infectious mononucleosis(im)and is implicated in burkitt lymphoma,nasopharyngeal carcinoma and x-linked lymphoproliferative syndrome.diagnosis of im based upon clinical manifesta¬tions in conjunction ...

ulcerative colitis (uc) is one type of inflammatory bowel disease (ibd). herpes viruses have been suggested as possible etiological agents of uc and crohn’s disease (cd). the aim of this study was to investigate the prevalence of herpes simplex virus (hsv), cytomegalovirus (cmv) and epstein-barr virus (ebv) in patients with uc in comparison with healthy subjects by using pcr technique. in this ...

conclusions the findings of the meta-epidemiological study support that ebv infection may increase the risk of breast cancer. nested case-control studies are required in the future. results a total of 20 case-control studies were selected, and the total numbers of subjects in the case and control groups were 1947 and 1010, respectively. the findings of this meta-analysis revealed that ebv infec...

Solid-organ transplantation is a therapeutic option for many end-stage diseases. One of the most common complications in the post-transplant period are different kind of infections. They are caused by some bacterial pathogens such as Legionella spp., Nocardia spp., Salmonella spp. and Listeria monocytogenes, many viral agents – Cytomegalovirus /CMV/, Herpes simplex virus / HSV/, Varicella-zoste...

Background: Breast cancer is the malignancy in humans and other mammals. Several risk factors are involved in their appearance such as higher hormone levels and obesity. Identification of a mouse mammary tumor virus supports a viral etiology for breast tumors in animals. Viruses have been implicated in the development of various cancers, but viral induction for formation breast cancer is contro...

Celiac disease (CD) is an autoimmune condition presenting with a wide variety of nonspecific gastrointestinal symptoms. It can be difficult to diagnose due the vagueness complaints such as diarrhea, anemia malabsorption, vitamin or electrolyte deficiencies, and/or failure thrive. This characterized by sensitivity ingested gluten-containing compounds. Blood tests used for screening, though confi...