An important reason to improve methods of isolating platelet-rich plasma (PRP) is the potential use of autologous platelet growth factors. In addition to discontinuous plasma separation, a second method for extraction of PRP has now become available, which can be performed directly by the surgeon. In this study, the suitability of the 2 methods of producing PRP was compared. Whole blood was dra...

BACKGROUND Platelet-rich plasma (PRP) is an autologous concentration of human platelets in plasma. In this paper, we aimed to investigate the effect of PRP on hair growth. METHODS Platelet-rich plasma and platelet-poor plasma were prepared by sterile centrifugation and injected into shaved dorsal skin of mice (n = 10). Saline injection was used in the control group. The length of randomly plu...

Background: Numerous studies have been published on the use of platelet-rich plasma (PRP) for knee osteoarthritis (OA), with conflicting results. Purpose: To determine fragility index (FI) and quotient (FQ) randomized controlled trials (RCTs) that evaluated PRP to treat OA. Study Design: Systematic review. Methods: RCTs evaluating efficacy injections OA from 2000 2020 were included analysis acc...

Background: Ovarian aging may be reversible. Platelet rich plasma (PRP) has growth factors that promote cellular proliferation and folliculogenesis. Recently published studies case reports suggest ovarian rejuvenation can done by PRP treatment. The objective of the study was to evaluate effect platelet on reserve markers such as anti mullerian hormone (AMH) antral follicle count (AFC) in sub fe...

Background: Platelet-rich plasma (PRP) is blood containing an above baseline level of platelets and growth factors. Recently, has come to the attention aesthetic surgeons, with burgeoning new applications ranging from hair restoration soft tissue augmentation. Injectable Poly-D,L-Lactic Acid (PDLLA) a biostimulator rather than traditional filler, which provides immediate volumetric improvement....

Partial thickness rotator cuff tears (PTRCTs) are a common pathology among shoulder disorders in people over 50 years.Treatment of PTRCTs remains controversial. Most studies on the treatment of PTRCTs have explained surgical techniquesor outcomes; few studies have centralized on the conservative and new management of PTRCTs, like treatmentwith Platelet-rich plasma (PRP). These case series study...

BACKGROUND Thrombin generation assay is a convenient and widely used method for analysis of the blood coagulation system status. Thrombin generation curve (TGC) is usually bell-shaped with a single peak, but there are exceptions. In particular, TGC in platelet-rich plasma (PRP) can sometimes have two peaks. OBJECTIVE We sought to understand the mechanism underlying the occurrence of two peaks...

Editorial Platelet rich plasma (PRP), also termed autologous platelet gel, plasma rich in growth factors (PRGF), platelet concentrate (PC), is essentially an increased concentration of autologous platelets suspended in a small amount of plasma after centrifugation. Basically, patient's blood is collected and centrifuged at varying speeds until it separates into 3 layers: platelet poor plasma (P...

BACKGROUND Platelet-rich plasma (PRP) has recently been postulated as a treatment for osteoarthritis (OA). Although anabolic effects of PRP on chondrocytes are well documented, no reports are known addressing effects on cartilage degeneration. Since OA is characterized by a catabolic and inflammatory joint environment, the authors investigated whether PRP was able to counteract the effects of s...

BACKGROUND Rotational atherectomy with the Rotablator catheter has improved percutaneous treatment of certain coronary atherosclerotic lesions, but the "no-reflow" phenomenon remains a serious complication. Because platelet activation by rotablation may contribute to the no-reflow phenomenon, we developed an in vitro system to test the effect of rotablation on platelets in the absence or presen...