By use of isolated canine hepatocytes and insulin analogs prepared by trypsin-catalyzed semisynthesis, we have investigated the importance of the aromatic triplet PheB24-PheB25-TyrB26 of the COOH-terminal B-chain domain of insulin in directing the affinity of insulin-receptor interactions. Analysis of the receptor binding potencies of analogs bearing transpositions or replacements (by Tyr, D-Ty...

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by a continual decline of cognitive function. No therapy has been identified that can effectively halt or reverse its progression. One hallmark of AD is accumulation of the amyloid-b peptide (Ab), which alone induces neuronal injury via various mechanisms. Data presented here demonstrate that prolonged exposure (1–24 hours) ...

Leaf spot disease caused by Cercospora beticola Sacc. is the most destructive foliar of beet. leaf controlled primarily fungicides because non-chemical alternatives do not provide commercially viable control. One ways reducing chemical application use different essential oils (EOs) or antagonistic plant growth-promoting rhizobacteria (PGPB). This study evaluates several EOs and PGPB belonging t...

To develop a new kind of thermistor with the negative temperature coefficient (NTC) behaviour, Cu/Mo co-doped YFeO3 based ceramics were prepared by wet-chemical synthesis and sintering at 1300?C. The orthorhombic perovskite structure was identified in all XRD analysis. possible valence states Fe, Cu Mo doped compounds examined X-ray photoelectron spectroscopy. By adjusting concentration Cu- Mo-...

in this article,we briefly analyse cognitive science and cognitive economics. generally, there are two main theories related to cognitive science and brain performance models. first theory which are inspired by computer and artifical intelligence and second the connectionist models. the connectionist theory is the most prevalent in cognitive science now. hayek and north ,the two nobel laureates...

High molecular weight glutenin subunits (HMW-GSs) play a major role in determining the dough quality of wheat. As D genome donor hexaploid wheat, Aegilops tauschii is an important genetic resource for wheat breeding. In present study, novel HMW-GSs from Ae. was identified and designated as Glu-Dt1. Multiple sequence alignment indicated that one cysteine mutated into arginine y-type subunit. Sit...

<p style='text-indent:20px;'>In this paper, we will study the emergent behavior of Kuramoto model with frustration on a general digraph containing spanning tree. We provide sufficient condition for emergence asymptotical synchronization if initial data are confined in half circle. As lack uniform coercivity digraph, apply node decomposition criteria [<xref ref-type="bibr" rid="b25">...