نتایج جستجو برای: b thalassemia
تعداد نتایج: 917848 فیلتر نتایج به سال:
Background: Thalassemia is a serious inherited blood disorder. Children and adolescent living with thalassemia major require lifelong repeated transfusions costly medicines for their survival. In India, β-thalassemia prevalence 3-4%. are basic pillars of society although they the most vulnerable part in view nutrition, education social life.Methods: Cross-sectional, observational study was cond...
One of the genetic features of the Sardinian population is the high prevalence of hemoglobin disorders. It has been estimated that 13% to 33% of Sardinians carry a mutant allele of the alpha-globin gene (alpha-thalassemia trait) and that 6% to 17% are beta-thalassemia carriers. In this population, a single mutation of beta-globin gene (Q39X, beta(0) 39) accounts for >95% of beta-thalassemia cas...
Objectives. Check with hematological data that the diagnosis and clinical grade of β-thalassemia intermedia can be established when a triplication genes alpha (αααanti 3.7) heterozygous are coherent. Methods. Retrospective study in which 73 patients Caucasian origin participated, who simultaneously showed tripling or quadrupling α β-thalassemia. Screening for most frequent α-thalassemia mutatio...
conclusions based on our results, it seems that there were no cases of obi among chronic hcv-infected patients with thalassemia and bleeding disorders, particularly hemophilia. however, to improve decisions concerning obi screening, especially in transfusion centers, and concerning the use of comprehensive screening methods, more original studies with more precise laboratory techniques and larg...
Background: Thalassemia is a set of inherited hematological illnesses caused by mutations in the genes that code for globin. Regular blood transfusions extend lives thalassemia patients, but they also increase danger blood-borne illness infections. Objective: The current study was conducted to check frequency and risk factors hepatitis B virus (HBV) infections among β major patients. Methods: o...
Abstract Background Thalassemia patients that are conventionally treated by a regular transfusion regimen are exposed to blood born viral infections.The aim of this study was to investigate the seroprevalence of hepatitis B virus (HBV), hepatitis C virus (HCV) , and human Immunodeficiency virus(HIV) among all multitransfused thalassemia patients in west north of Iran. Material and methods A...
BACKGROUND Hemoglobinopathies are a group of inherited disorders of hemoglobin synthesis. It could be formed a fatal scenario in concern of lacking of actual information. Beside this, ABO and Rh blood grouping are also important matter in transfusion and forensic medicine and to reduce new born hemolytic disease (NHD). MATERIALS AND METHODS The spectrum and prevalence of various hemoglobinopa...
The protein composition of ghosts. inside-out vesicles (by). and membrane skeletons (MS) of erythrocytes (ABC) from splenectomized (spx) and nonsplenectomized (nonspx) patients with $-thalassemia major and $-thalassemia intermedia was determined. Ghosts from spx thalassemia intermedia patients had a significant increase in their globin content (which was mostly heme reactive) and contained extr...
Thalassemia is a group of inherited blood disorders due to the reduction or absence globin chain synthesis which can cause hemolytic anemia. β-thalassemia major severe type thalassemia, in patients require lifelong transfusions for survival. Extravascular hemolysis on spleen results splenomegaly, meanwhile, extramedullary hematopoiesis causing hypersplenism develop beta-thalassemia patients. Hy...
INTRODUCTION Thalassemia patients are prone to the hepatitis C, B, and HIV virus, due to their constant need to receive blood transfusions. Therefore, this research was aimed to determine the epidemic of the aforementioned diseases in thalassemia patients of Shahid Mohammadi Hospital of Bandar Abbas, Iran. METHODS This cross-sectional study was carried out on thalassemia patients visiting the...
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