Regardless of ethnicity or geographical distribution, Wiskott-Aldrich syndrome affects 1 in every 100,000 live male births. It has been established that may potentially be a source autoimmune illnesses and reticuloendothelial malignancies, even though most patients present with the traditional triad thrombocytopenia, eczema, recurrent bacterial infections. This case report introduces 4-year-old...

Chronic lymphocytic leukemia is frequently associated with immune disturbances. The relationship between chronic lymphocytic leukemia and autoimmune cytopenias, particularly autoimmune hemolytic anemia and immune thrombocytopenia, is well established. The responsible mechanisms, particularly the role of leukemic cells in orchestrating the production of polyclonal autoantibodies, are increasingl...

Introduction Chronic granulomatous disease (CGD) is a primary immune deficiency that characterized with recurrent infections and granuloma formation. A variety of autoimmune disorders and immune-mediated phenomena such as inflammatory bowel disease, discoid lupus erythematous, juvenile idiopathic arthritis, Ig A nephropathy, sarcoidosis, rheumatoid arthritis, idiopathic thrombocytopenia, eosino...

Immune thrombocytopenia (ITP) is an entity characterized by a platelet count of less than 100 × 10(9)/L in the absence of other causes of thrombocytopenia, such as viral infections, rheumatic diseases, or drugs. Grave's disease is also an autoimmune condition in which thrombocytopenia is often observed. Moreover, in the literature, many reports show a marked interference of the thyroid dysfunct...

That a humoral factor was the causative agent in idiopathic thrombocytopenic purpura was suggested nearly 30 years ago after the observation that mothers with the disease often give birth to children who develop transient thrombocytopenia.1 Maternal platelet autoantibodies were presumed to pass into the fetal circulation. With present techniques2 3 platelet autoantibodies are detectable in most...

Brucellosis is still endemic and a significant public health problem in many Mediterranean countries, including Greece. It is a multisystemic disease with a broad spectrum of clinical manifestations including hematological disorders, such as anemia, pancytopenia, leucopenia, and thrombocytopenia. Thrombocytopenia is usually moderate and attributed to bone marrow suppression or hypersplenism. Ra...

Thrombocytopenia is defined as a platelet count of less than 100,000 platelets per microlitre (mcL). Thrombocytopenia develops in approximately 6-7% of women during pregnancy and at least 3% of these cases are caused by immunological platelet destruction. Herein, we present a pregnant woman who develops at the first trimester autoimmune thrombocytopenia purpura associated with positive antiphos...

Sjögren's syndrome (SS) is an autoimmune disease characterised by a chronic inflammatory response mainly localised to the lachrymal and salivary glands. Haematological abnormalities are common, although they rarely have clinical significance. Here, we report a patient with SS and thrombocytopenia caused by albendazole. Haematological abnormalities such as thrombocytopenia are seen in approximat...