background autoimmune hepatitis (aih) is a form of chronic hepatitis with unclear causative factors and is characterized by immunological and auto-immunological manifestations. several extrahepatic manifestations, such as other autoimmune disorders, are associated with aih. aih with dermatological conditions as the initial manifestation is rare. we report the case of aih in which erythema nodos...

introduction: multiple sclerosis (ms) has been recognized as a common neurodegenerative disease that occurs after an auto reactive t cells against myelin antigens.  demyelination and inflammation are the main features of this disease. the anti-inflammatory and neuroprotective roles of bone marrow-derived mesenchymal stem cells (bm-mscs) have been considered as a suitable treatment against autoi...

Inflammation is a physiological event that protects tissues from infection and injury. Chronic inflammation causes immune cell over activation sustained release of inflammatory cytokines chemokines cause pathologic conditions including autoimmune diseases. Heavy metals exposure affects innate adaptive systems through triggering responses. It seems extended responses could accelerate heavy metal...

Mammalian immune responses are intended to eradicate microbial pathogens and thus protect individuals from the harmful effects of such infections. However, unresolved inflammation can be devastating to the host and cause tissue damage and organ malfunction. Immune responses can even mistakenly target self-antigens and mediate autoimmune inflammation. Consequently, a variety of cellular and mole...