نتایج جستجو برای: autoimmune disorders
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Autoimmune disease occurs when the immune system attacks self-molecules as a result of a breakdown of immunologic tolerance to autoreactive immune cells. Many autoimmune disorders have been strongly associated with genetic, infectious, and/or environmental predisposing factors. Comprising multiple disorders and symptoms ranging from organ-specific to systemic, autoimmune diseases include insuli...
N Engl J Med 2004;350:2068-79. Copyright © 2004 Massachusetts Medical Society. he autoimmune polyendocrine syndromes are diverse, and their diversity is a characteristic that is both clinically important and instructive when their basic immunologic features are considered (Table 1). 1-4 These syndromes include monogenic disorders (such as autoimmune polyendocrine syndrome type I, which has clas...
BACKGROUND Common autoimmune disorders tend to coexist in the same subjects and to cluster in families. METHODS We performed a cross-sectional multicenter study of 3286 Caucasian subjects (2791 with Graves' disease; 495 with Hashimoto's thyroiditis) attending UK hospital thyroid clinics to quantify the prevalence of coexisting autoimmune disorders. All subjects completed a structured question...
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