background: sj?gren’s syndrome is an autoimmune syndrome involving the exocrine glands specially the salivary and lacrimal glands leading to xerostomia and xerophtalmia. this paper presents a case with primary sj?gren’s syndrome that severe dental caries were the first clinical manifestation. case presentation: a 42-year-old man was referred to the school of dentistry, tehran university of medi...

background this prospective study was designed to examine the role of fibrosis staging on selection and success of treatment options for autoimmune hepatitis (aih). materials and methods the project was conducted on 110 selected aih patients who, based on the results of liver biopsy, had been assigned into one of the three groups (mild, stages 1 and 2, moderate, stages 3 and 4, and severe, stag...

high cortisol level in endogenous cushing’s syndrome suppresses the immune system and after treatment there may be an over activity of immune reaction leading to autoimmune diseases mostly thyroid and rheumatologic disorders. this is the second reported case of multiple sclerosis developing after treatment of cushing’s syndrome. a 42-year old man is reported who presented with bone fracture and...

a 62-year-old woman complaining of severe malabsorption was diagnosed with celiac disease based on the findings of flat, small intestinal mucosa and hla-dq2 positivity, although celiac serology was negative. this diagnosis was questioned due to the lack of clinical and histological improvement after a long period of strict gluten-free diet. the detection of enterocyte autoantibodies guided to t...

psoriasis is a chronic, inflammatory and proliferative skin disease that has a wide distribution throughout the world. the immune system plays a critical role in developing this disease. in this survey, we have studied 50 patients suffering from psoriasis and 50 control subjects for various immunological factors, simultaneously. anti-stratum corneum (sc) antibody was evaluated by immunofluoresc...

autoimmune pancreatitis is a fibro-inflammatory form of chronic pancreatitis. it is diagnosed by the combination of imaging studies such as a ct scan and pancreatography, laboratory analyses that include igg4 and/or autoantibodies, histopathological evaluations and positive response to corticosteroid therapy. we report the case of a 41-year-old female with a history of jaundice and increasing a...

an 11-year-old female patient with autoimmune hepatitis (aih) was referred to our rheumatology clinic due to her current musculoskeletal manifestations. the patient had been diagnosed with aih 3 months previously, based on jaundice and impaired liver function tests, and she had been treated with low-dose prednisolone and azathioprine. she presented with malaise, arthritis, a malar rash on the f...

introduction to define the clinical features, biochemical and histological findings and outcome of three forms of autoimmune hepatitis.   materials and methods in a cross sectional study between november 2001 to january 2008 in tehran and mashhad university of medical sciences, 61 children who diagnosed as aih (40 girls and 21 boys) have been analyzed for their clinical, serological, and histol...

this paper is by terry kemp. she is a midwife with 10 years record of service. in this paper she speaks about her own experience which had burdened her in that condition. herpes gestation is a rare condition and has been defined in books related to autoimmune gestation disease. if your reaction after reading the title of this paper was just shrugging your shoulders and accepting it as a viral i...