Autistic-spectrum conditions and psychotic-spectrum conditions (mainly schizophrenia, bipolar disorder, and major depression) represent two major suites of disorders of human cognition, affect, and behavior that involve altered development and function of the social brain. We describe evidence that a large set of phenotypic traits exhibit diametrically opposite phenotypes in autistic-spectrum v...

Introduction Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by social and communication deficits restricted repetitive or stereotyped behaviours. The prevalence of ASD has been thought to be higher in men, which may reflect aspects the own aetiology disorder. Still, it also associated with misdiagnosis missed diagnosis females autism due specific phenotypic traits...

background: despite many efforts, the etiology of autism remains unknown. food allergy has been suggested as a pathogenic factor in autism spectrum disorder (asd). our aim in this study was to determine whether food allergy could be considered as a risk factor for autistic children. methods: thirty-nine autistic children were examined by the skin prick test (spt), and total serum ige was evalua...

autistic disorders (ads) are neuro-developmental disorders in the category of pervasive developmental disorders chiefly described by three main deficits: 1) deviant communication, 2) impaired reciprocal social interaction, and 3) limited, repetitive and stereotypic patterns of behaviors or interests 1. the world-wide prevalence of ads is estimated to be 62/10,000 1. although various treatment r...

autism is a complex neuropsychiatric disorder that manifests in early childhood. although the etiology is unknown yet but, new hypothesis focused on identifying the key genes related to autism may elucidate its etiology. the main objective of the present study was to verify the value of karyotyping in autistic children and identifying association between chromosome abnormalities and autism.we e...

the aim of the present study was to compare the broader autism phenotype in iranian parents of children with autism spectrum disorders and parents of typically developing children.parents of children with asd and parents of typically developing children were asked to complete the persian version of the autism spectrum quotient (aq). in the asd group, families included 204 parents (96 fathers an...

BACKGROUND Urinary metabolite measurements are often normalized to levels of the ubiquitous metabolite creatinine (CRT) to take account of variations in fluid export. Following CRT normalization, excesses of porphyrins and isoprostanes have been reported in the urines of children with neurodevelopmental disorders. It was suggested (Whiteley et al., 2006, Pediatr. Int. 2006; 48: 292-297) that ur...

Dental treatment of patients with Autism Spectrum Disorders (ASD) can be complicated because of the presence of behavioural unpredictability. This article reviews the present literature on the issues dealt with children with autistic spectrum disorder from the dental perspective. The prevalence of autism is rising worldwide. Consequently, dentists will find an increasing number of such children...

Little is known about the prevalence of violence and autistic spectrum disorders. This article reviews findings of current research on Asperger's disorder and violence. Criteria for diagnosing Asperger's disorder are given. Three cases are presented in which defendants with diagnosed Asperger's disorder were charged with murder. Specific symptoms in this disorder are discussed as they relate to...