Atypical hemolytic-uremic syndrome (HUS) is a rare life-threatening disorder characterized by microangiopathic hemolytic anemia, thrombocytopenia, and ischemic injury to organs, especially the kidneys. Microvascular injury and thrombosis are the dominant histologic findings. Complement activation through the alternative pathway plays a critical role in the pathogenesis of atypical HUS. Genetic ...

hydatid cyst is a zoonotic disease that is common in the mediterranean region. thoracic wall, rib or extrapulmonary intrathoracic localization of the cysts is very rare. giant extrapulmonary intrathoracic hydatid cysts can lead to both diagnostic and treatment difficulties and can be confused with tumor. we present a case of a hydatid cyst with thoracic wall involvement mimicking tumor. we conf...

Pompe disease is a rare autosomal recessive lysosomal storage disease caused by defi ciency of acid α-glucosidase (GAA). This defi ciency results in glycogen accumulation in the lysosomes, leading to lysosomal swelling, cellular damage, and organ dysfunction. In early onset patients (the classic infantile form), this glycogen accumulation leads to death, usually before the age of 1 year. Some p...

To compare and characterize major depressive disorder (MDD) subtypes (i.e., pure atypical, melancholic mixed atypical-melancholic) depression symptoms in persons with multiple sclerosis (PwMS) without MS (Pw/oMS) fulfilling the DSM-5 criteria for a past 12-month MDD. MDD PwMS (n = 92) from Swiss Multiple Sclerosis Registry was compared Pw/oMS 277) community-based study. Epidemiological diagnose...

BACKGROUND Since 2002, an active surveillance program for transmissible spongiform encephalopathy in small ruminants in European Union countries allowed identification of a considerable number of atypical cases with similarities to the previously identified atypical scrapie cases termed Nor98. CASE PRESENTATION Here we report molecular and neuropathological features of eight atypical/Nor98 sc...