OBJECTIVE Little is known about the relative contributions of modifiable risk factors to overall diabetes mortality. The purpose of the current study is to 1) assess the association between modifiable risk factors and all-cause mortality among a nationally representative sample of individuals with diabetes and 2) determine the population-attributable risk percent (PAR%) for these factors. RES...

OBJECTIVE To support tobacco control policies in Korea by providing the estimated annual economic burden attributed to cigarette smoking. METHODS The following two different approaches were used to estimate the cost: "disease specific" and "all causes". In the disease specific approach, we focused on estimating direct and indirect costs involved in treatments of cardiovascular, respiratory, a...

BACKGROUND The results of studies on the association between prehypertension (blood pressure 120 to 139/80 to 89 mm Hg) and coronary heart disease (CHD) remain controversial. Furthermore, it is unclear whether prehypertension affects the risk of CHD in Asian and Western populations differently. This meta-analysis evaluated the risk of CHD associated with prehypertension and its different subgro...

OBJECTIVE Exposure to environmental tobacco smoke (ETS) is associated with a variety of health effects, including lung cancer and ischaemic heart disease. The objective of this study was to estimate the number of deaths caused by exposure to ETS among non-smokers in Spain during the year 2002 METHODS Prevalence of ETS exposure among never smokers was gathered from three region based health in...

background: water, sanitation and hygiene have a very important role in public health. poor sanitation is the cause of water contamination, which causes many types of diseases. the aim of this paper was to present the attributable death and disability adjusted life year (dalys) of untreated water and insanitary environments from 1990 to 2010 in iran.   methods: in the global burden of disease 2...

Resequencing is an emerging tool for identification of rare disease-associated mutations. Rare mutations are difficult to tag with SNP genotyping, as genotyping studies are designed to detect common variants. However, studies have shown that genetic heterogeneity is a probable scenario for common diseases, in which multiple rare mutations together explain a large proportion of the genetic basis...

BACKGROUND A possible association between the TACC3 rs798766 polymorphism and urinary bladder cancer risk has been indicated in published literature. We performed this meta-analysis as a synthesis of all relevant data to summarize currently available evidence and to provide estimation with increased precision. METHODS EMBASE, PubMed, Google Scholar, and Wanfang Data were searched. "rs798766" ...