To the Editor: Methylphenidate is the most commonly prescribed medication to treat attention-deficit/hyperactivity disorder (ADHD) in children and adolescents. The long-term impact of methylphenidate on adult height remains debated1 because a significant negative impact on children’s growth has been suggested. The Multimodal Treatment Study of ADHD showed that children receiving methylphenidate...

Attention-deficit/hyperactivity disorder (ADHD) is a common psychological disorder for which the preferred treatment is with stimulants (methylphenidate). With medication administration to young children becoming exceedingly common, it is important to investigate the neurodevelopment consequences of doing so. Much of the imaging literature that suggests neuroanatomical differences in ADHD patie...

The symptoms of attention-deficit/hyperactivity disorder (ADHD) are characterized by inattention and hyperactivity-impulsivity. It is a common childhood neurodevelopmental disorder that often persists into adulthood. Improvements in ADHD symptoms using psychostimulants have been recognized as a paradoxical calming effect. The psychostimulant methylphenidate (MPH) is currently used as the first-...

Attention deficit/hyperactivity disorder (ADHD) is one of the most common psychiatric disorders in children with several complications. This study was conducted to investigate the effect of adding ferrous sulfate to methylphenidate in decreasing ADHD symptoms. This study was a double-blind, randomized clinical trial. In this study, 42 nonanemic children with ADHD and serum ferritin below 30 mg/...

BACKGROUND Attention-deficit hyperactivity disorder (ADHD) is highly prevalent in prison inmates, but pharmacological treatment has not yet been evaluated in this group. AIMS To evaluate osmotic-release oral system (OROS) methylphenidate in adult male long-term prison inmates with ADHD. METHOD Randomised, double-blind, placebo-controlled 5-week trial, followed by 47-week open-label extensio...

Attention Deficit/Hyperactivity Disorder (ADHD) is characterised by developmentally inappropriate levels of inattention, impulsivity and hyperactivity. As might be expected of a disorder in which inhibitory deficits form part of the diagnostic criteria, deficits in response inhibition in ADHD have been evidenced in a number of studies. To date, the tasks used in such studies have required parti...

ackground: We examined the effect of prolonged methylphenidate (MPH) treatment on the functional neuroanatomy of executive unctioning in adult men with attention-deficit/hyperactivity disorder (ADHD). ethods: Positron emission tomography with [O] water measured alterations of regional cerebral blood flow (rCBF) during the aced Auditory Serial Addition Task and a control task in 10 ADHD and 11 n...

Objective To compare children with attention-deficit/hyperactivity disorder (ADHD), before and after the use of methylphenidate, and a control group, using tests of working memory, inhibition capacity and mental flexibility. Methods Neuropsychological tests were administrated to 53 boys, 9-12 years old: the WISC-III digit span backward, and arithmetic; Stroop Color; and Trail Making Tests. Th...

PURPOSE Methylphenidate (MPH) is an effective medication for the treatment of attention deficit hyperactivity disorder (ADHD). However, about 30% of patients do not respond to or are unable to tolerate MPH. Based on previous findings, we hypothesized that great variability in response time (RT) among Korean children with ADHD on a computerized continuous performance attention test would be rela...