نتایج جستجو برای: atp binding cassette transporter a1
تعداد نتایج: 528933 فیلتر نتایج به سال:
ATP binding cassette transporter A1 (ABCA1) limits the formation of high density lipoproteins (HDL) as genetic loss ABCA1 function causes virtual HDL deficiency in patients with Tangier disease. Mice a hepatocyte-specific knockout (Abca1 HSKO) have 20% wild type (WT) plasma HDL-cholesterol levels, suggesting major contribution hepatic to phenotype. Whether sphingolipids are reduced disease and ...
OBJECTIVE We aim to identify the impact of endogenous cholesteryl ester transfer protein (CETP) activity on plasma capacity to mediate free cholesterol efflux from human macrophages. METHODS AND RESULTS Endogenous plasma CETP activity was measured in a population of 348 women. We defined a low CETP group corresponding to subjects displaying an endogenous plasma CETP activity within the first ...
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