abstract         background and objective: the relationship between diabetes mellitus and increased risk of cardiovascular diseases has been demonstrated. the aim of this study was to determine the fatty acid profile of epicardial adipose tissue in diabetic and non-diabetic patients with cardiovascular disease.          methods: in this study, 28 diabetic and 40 nondiabetic patients were evalua...

background & objectives: several epidemiological studies have indicated factors such as leptin level, adiponectin and plasma adiponectin-to-leptin index to be the predicting biomarkers for cardiovascular diseases. given the importance of healthy nutrition and adequate exercise in reducing the risk of atherosclerosis, this study aimed to investigate the effects of fasting and aerobic exercise on...

the aim of this study was to investigate the iron concentrations in serum and carotid plaque in patients with different morphology of carotid atherosclerotic plaque and compared with other metal ions. carotid endarterectomy due to the significant atherosclerotic stenosis was performed in 91 patients. control group consisted of 27 patients, without carotid atherosclerosis. atherosclerotic pla...

Abstract Leukocytes and resident cells in the arterial wall contribute to atherosclerosis, especially at sites of disturbed blood flow. Expression endothelial Tie1 receptor tyrosine kinase is enhanced these sites, attenuation its expression reduces atherosclerotic burden decreases inflammation. However, Tie2 function atherosclerosis unknown. Here we provide genetic evidence from humans an mouse...

the polymerase chain reaction (pcr) as applied to detection of a foreign dna in clinical specimens could provide a sensitive instrument for rapid detection of viral dna persisting in tissues of patients suspected of latent infection. human cytomegalovirus (hcmv) dna was found in arterial plaques of patients with atherosclerotic lesions using a pcr assay with nested primer oligonucleotides deriv...

abstract background: atherosclerosis and subsequent coronary artery disease is the leading cause of death in iranian population. high serum lipid levels, especially the elevated level of low-density lipoprotein (ldl), have been shown to be strongly related to the development of atherosclerosis. the relationship between dietary glycemic index (gi) and lipid profile, particularly in nonwestern po...

background : the aim of this study was to detect fungi in atherosclerotic plaques and investigate their possible role in atherosclerosis. methods : coronary atherosclerotic plaques specimen were obtained from patients with atherosclerosis. direct exami-nation, culture, histopathology study, pcr and sequencing were performed to detect/identify the mycotic elements in the plaques. age, sex, smoki...

Heme oxygenase-2 (HO-2) is a critical antioxidative stress enzyme found in endothelial cells and adventitialnerves. This enzyme in conjunction with other HOs (1 and 3) metabolize heme molecule into ferrous iron,carbon monoxide (CO), and biliverdin which is further converted to bilirubin. Both biliverdin and bilirubin arepotent antioxidants, reducing the risk of atherosclerosis...

Atherosclerosis is a chronic inflammatory disease. It still the leading cause of mortality and morbidity in world. Inflammation vessels plays most important role pathogenesis atherosclerosis. Many studies have been emphasized that Chlamydia pneumoniae triggers inflammation associated with stated chlamydial infections are asymptomatic around 40% adult individuals infected. has different subgroup...