نتایج جستجو برای: associated lipocalin
تعداد نتایج: 1521908 فیلتر نتایج به سال:
objective(s): lupus nephritis (ln) is the main cause of mortality and disability in systemic lupus erythematosus (sle) patients. therefore, utilizing a reliable and non-invasive method for serial measurements of renal function seems to be necessary. the aim of this study was to evaluate the role of urinary lipocalin-2 as a biomarker of renal involvement in sle patients. materials and methods:...
BACKGROUND Lipocalin-2, a 25-kDa secreted glycoprotein, is a useful biomarker for early detection of various renal injuries. Because lipocalin-2 is abundantly expressed in adipose tissue and liver, we investigated its relevance to obesity-related pathologies. METHODS We used real-time PCR and in-house immunoassays to quantify the mRNA and serum concentrations of lipocalin-2 in C57BL/KsJ db/db...
Introduction: Obesity and hypertension are associated with organ complications, including kidney diseases. It is necessary to search for the methods of early detection these complications. Aim: The aim study was assess renal function in obese adolescents, based on lipocalin-2 cystatin C levels relation creatinine, estimated glomerular filtration rate leptin levels. Materials methods: included 7...
Lipocalin 2, an iron-siderophore-binding protein, converts embryonic kidney mesenchyme to epithelia. We found that lipocalin 2 could also convert 4T1-Ras-transformed mesenchymal tumor cells to an epithelial phenotype, increase E-cadherin expression, and suppress cell invasiveness in vitro and tumor growth and lung metastases in vivo. The Ras-MAPK pathway mediated the epithelial to mesenchymal t...
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