asthma is a complex and multifactorial disorder. several studies have reported association between different hla- dqb1 and hla- drb1 alleles and allergic asthma. the aim of the present study was to investigate the association of hla-class ii alleles and haplotypes, with total serum ige and the results of the skin prick test in iranian children with allergic asthma. a total of 112 patients with ...

Antibodies to merozoite surface antigens (MSPs), the primary targets of malaria vaccine research, are associated with low morbidity. However, few studies have looked at implications their variations on evolution clinical-biological forms severe malaria.

Background A specific feature of the autoimmune response in rheumatoid arthritis (RA) is presence anti-citrullinated protein antibodies (ACPAs) patient sera. These can appear several years before disease onset and are involved development RA. Objective We performed proteomic analysis by mass spectroscopy to identify novel citrullinated antigens autoantibodies RA patients. Methods Polypeptides i...

While first and foremost considered a respiratory infection, COVID-19 can result in complications affecting multiple organs. Immune responses both protect against the disease as well drive it. Insights into these responses, specifically targets being recognised by immune system, are of vital importance understanding side effects associated pathologies. The body’s adaptive immunity recognises re...

background: tumor associated antigens can be viably used to enhance host immune response.objectives: the immunomodulatory effect of biogenic selenium nanoparticles (senps) was compared between treated and untreated mice with crude antigens of 4t1 cells.materials and methods: female inbred balb/c mice (60) were injected by cancinogenic 4t1 cells causing breast cancer. after 10 days, all tumor be...

using complement fixation technique, serial serum samples from 15 patients undergoing surgical removal of malignant tumors were assayed for the presence of tumors antibodies against the cellular fractions of both normal and carcinomatous tissue. antibody responses against tumor associated antigens were detected in four cases. in all cases antibody activity was directed only against the supernat...

The adaptive immune response to severe acute respiratory coronavirus 2 (SARS-CoV-2) is important for vaccine development and in the recovery from disease 2019 (COVID-19). Men cancer patients have been reported be at higher risks of contracting virus developing more forms COVID-19. Prostate (PCa) may associated with both these risks. We show that CD4 + T cells SARS-CoV-2-unexposed hormone-refrac...

background : immunological response of host and parasite play a key role in developing vaccina­tion and immunization. the present study deals with the immune response and effecter mechanism, which was confirmed by migration inhibition factor (mif).  methods : the present work was conducted in parasitological lab of postgraduate department of zool­ogy, government holkar science college, indore (...