Novel innovative catalytic systems such as hydrogen-bond donors and thiourea hybrid catalysts have been developed for the asymmetric synthesis of biologically important pharmaceuticals natural products. Benzothiadiazines possess a stronger donor ability compared to thioureas exhibit remarkable performance activation ?,?-unsaturated amides. Hybrid (bearing an arylboronic acid ammonium salt) effi...

Herein, we report a ruthenium‐catalyzed ketone directed ortho‐arylation wherein the addition of bidentate NC‐type ligand, most effectively 2‐(o‐tolyl) pyridine, significantly enhances C‐H arylation reaction. Various aryl‐alkyl ketones, including cyclic, aliphatic, and heterocyclic ones, are competent substrates, arylboronic acid esters were used as aryl sources. However, substitution with OMe C...

Chitin is the most abundant N-containing polysaccharide in nature and d-glucosamine one of successful commercial monomer products current market. Here we reported an arylboronic acids catalyzed upgrade glucosamines aqueous solution for deoxyfructosazine which important high-value compound pharmaceutical food industries, as well a promising bio-based platform molecule speciality chemicals sustai...

Highly selective C(sp²)-C(sp²) cross-coupling of dihalogenated hydrocarbons comprising C(sp²)-Br and C(sp³)-Cl bonds with arylboronic acids is reported. This highly selective coupling reaction of the C(sp²)-Br bond is successfully achieved using Pd(OAc)₂ and PCy₃·HBF₄ as the palladium source and ligand, respectively. A series of chloromethyl-1,1'-biphenyl compounds are obtained in moderate-to-e...

Cationic palladium(II) complexes have been found to be highly reactive towards aromatic C-H activation of arylureas at room temperature. A commercially available catalyst [Pd(MeCN)4](BF4)2 or a nitrile-free cationic palladium(II) complex generated in situ from the reaction of Pd(OAc)2 and HBF4, effectively catalyzes C-H activation/cross-coupling reactions between aryl iodides, arylboronic acids...

The CuOAc-catalyzed reaction of internal alkynoates with arylboronic acids proceeded under mild conditions to yield trisubstituted cinnamates stereoselectively.

The addition of arylboronic acids, ArB(OH)2, to N-phenylsulfonyl aldimines, RCH=NSO2Ph (R=alkyl, aryl, 1-alkenyl), giving R(Ar)CHNHSO2Ph was carried out at 95 °C in the presence of a rhodium catalyst. [Rh(cod)(MeCN)2]BF4 (3 mol%) was found to be the best catalyst for aryl aldimines and Rh(acac)(coe)2/i-Pr3P for alkyl and 1-alkenyl aldimines. The analogous reactions of arylboronic esters, such a...

A highly efficient heterogeneous copper-catalyzed chlorodeboronation of arylboronic acids with inexpensive N-chlorosuccinimide (NCS) was achieved in MeCN in the presence of 10 mol% of L-prolinefunctionalized MCM-41-immobilized copper(I) complex [MCM-41-L-proline-CuCl] under mild conditions, yielding a variety of aryl chlorides in excellent yields. This method proved to be tolerant of a broad ra...

N-Alkoxycarbonyl / carbamoylmethyl substituted 1H-imidazol-2-yliden-Pd (II) complexes (Cat-1-5) were used for the first time as catalysts in Suzuki-Miyaura reaction between aryl bromides and arylboronic acids. All screened found to be excellent selected coupling 4-bromobenzaldehyde phenylboronic acid at room temperature. Cat-3 was shown most efficient one optimisation of conditions determining ...