changes associated with pathological states. Nanodevices like carbon nanotubes to locate and deliver anticancer drugs at the specific tumor site are under research. Nanotechnology promises construction of artificial cells, enzymes and genes. This will help in the replacement therapy of many disorders that are due to deficiency of enzymes, mutation of genes or any repair in the synthesis of prot...

Syntheses of biomimetic low-molecular weight poly-(R)-3-hydroxybutanoate mediated by three types of supramolecular catalysts are presented. The utility of these synthetic polyesters for preparation of artificial channels in phospholipid bilayers capable of sodium and calcium ion transport across cell membranes, is discussed. Further studies on possible applications of these bio-polymers for man...

The use of mind altering drugs has become a major characteristic of American social behavior, and in our complex technological society is is unlikely that man will ever be able to eliminate his desire or need for "artificial paradises" as a means of coping with the stresses of daily existence. Unfortunately, when individuals use drugs, many also tend to abuse them with subsequent disruption of ...

Ultraviolet radiation is considered the main environmental physical hazard to the skin. It is responsible for photoaging, sunburns, carcinogenesis, and photodermatoses, including drug-induced photosensitivity. Drug-induced photosensitivity is an abnormal skin reaction either to sunlight or to artificial light. Drugs may be a cause of photoallergic, phototoxic, and photoaggravated dermatitis. Th...

We investigate which of two Artificial Intelligence techniques is superior at making predictions about complex carcinogen systems. Artificial Neural Networks are shown to provide good predictions of carcinogen toxicology bands for drugs which are themselves used to treat cancerous cells, by using a novel system of molecular descriptors derived from the molecules’ mass spectrometry intensities, ...

Recently, profiling the chemical substances in illegally distributed drugs has been needed in order to reveal the drug channels. However, this kind of profiling is often difficult because such drugs contain various kinds of impurities and the quantity of these impurities changes. Due to these circumstances, several methods, including a slightly revised ICA (Independent Component Analysis) by a ...

A method of feature extraction based on principal component analysis (PCA) to identify drugs packed in anthropomorphic phantom was proposed. An energy dispersive X-ray diffraction spectrometer was used to acquire the spectra of drugs and the other materials. Features of spectra were extracted by PCA which excels in analyzing highdimensional data. Furthermore, the number of principal components ...

The fate of various emerging contaminants as well as priority pollutants from the European Union Water Framework directive was examined along a complex combination of natural and engineered processes used to produce drinking water downstream of a major metropolitan area. The sampling points examined comprised Seine river water downstream of the Paris area, water from a primary well after bank f...