نتایج جستجو برای: aqueous suppressants
تعداد نتایج: 84397 فیلتر نتایج به سال:
INTRODUCTION Two replicate randomized, placebo-controlled six-month trials (RCTs) and an open-label treatment extension (OLE) comprised the pegloticase development program in patients with gout refractory to conventional therapy. In the RCTs, approximately 40% of patients treated with the approved dose saw complete response (CR) of at least one tophus. Here we describe the temporal course of to...
abstract amino acids are building blocks of proteins, and play a vital role in living beings existence and their functionality. the interaction of these compounds with metal ions is of great importance to biochemists, and chemists, because their functions can be utilized as a model in understanding enzymes mechanism for transport of metal ions to tissues. among twenty essential amino acids w...
Previous work on the vitamin B12 content of the aqueous humour (Phillips, Ainley, van Peborgh, Watson-Williams, and Bottomley, I968) suggests that the levels found in a series of mainly elderly patients (mean: 299 pg./ml.) are of the same order as those found in cerebrospinal fluid (mean: 21 pg./ml.) (Kidd, Gould, and Thomas, I963). As an extension of this study, the response of aqueous vitamin...
Many patients with gout have comorbidities, including hypertension and chronic kidney disease (CKD). The goals when treating gout are no different in these patients, but the choice and dosage of drugs may need to be modified.
OBJECTIVE To investigate the efficacy and safety of lesinurad in combination with febuxostat in a 12-month phase III trial in patients with tophaceous gout. METHODS Patients with serum urate (UA) ≥8.0 mg/dl (≥6.0 mg/dl with urate-lowering therapy) and ≥1 measurable target tophus were given febuxostat 80 mg/day for 3 weeks before randomization to receive lesinurad (200 or 400 mg daily) or plac...
The past 20 years have seen gastrin attain true hormonal status. Its structure has been characterized, it has been synthesized, radioimmunoassays for its measurement in blood and tissues have been developed and its physiology and metabolism elucidated. Of much interest to clinicians has been the association between gastrin and tumours of the pancreas (gastrinomas) and atrophic gastritis. The ad...
Vertigo is a sense of spinning dizziness. There no ideal medicine for treatment vertigo and The duration dizziness/vertigo: attacks may last seconds or minutes (as in vestibular paroxysm) hours Menière’s disease migraine). Diagnosis remains challenge many physicians. Many drugs produce dizziness side effects such as some antibiotics , diuretics, mucolytics NSAIDs. Symptoms are usually managed w...
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