Bolter, Chris P., and Suzanne J. Wilson. Influence of right atrial pressure on the cardiac pacemaker response to vagal stimulation. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R1112–R1117, 1999.—We have recently shown that the intrinsic rate response to an increase in right atrial pressure is augmented when cardiac muscarinic receptors are activated. This present study exami...

Li, Hongfei, Zermeena M. Marshall, and A. Richard Whorton. Stimulation of cystine uptake by nitric oxide: regulation of endothelial cell glutathione levels. Am. J. Physiol. 276 (Cell Physiol. 45): C803–C811, 1999.—Nitric oxide (NO) is known to produce some of its biological activity through modification of cellular thiols. Return of cellular thiols to their basal state requires the activity of ...

Hurley, Bernard R., Harold G. Preiksaitis, and Stephen M. Sims. Characterization and regulation of Ca21dependent K1 channels in human esophageal smooth muscle. Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G843– G852, 1999.—We examined the properties of K1 channels in smooth muscle cells dissociated from human esophagus using patch-clamp recording in the cell-attached configuration. Th...

Kwon, Hyeok Y., Ta-Min Chang, Kae Y. Lee, and William Y. Chey. Vagus nerve modulates secretin binding sites in the rat forestomach. Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G1052–G1058, 1999.—Secretin is well known for its inhibitory action on gastric motility. It has been reported that secretin in a physiological dose inhibits gastric motility through mediation by the vagal affer...

Liu, Gele, Leonard Kleine, Rania Nasrallah, and Richard L. Hébert. Bradykinin inhibits ceramide production and activates phospholipase D in rabbit cortical collecting duct cells. Am. J. Physiol. 276 (Renal Physiol. 45): F589–F598, 1999.—Recent reports suggest that inflammatory cytokines, growth factors, and vasoconstrictor peptides induce sphingomyelinase (SMase) activity. This results in the h...

Leclercq-Meyer, Viviane, Marcel M. Kadiata, and Willy J. Malaisse. Stimulation by 2-deoxy-D-glucose tetraacetates of hormonal secretion from the perfused rat pancreas. Am. J. Physiol. 276 (Endocrinol. Metab. 39): E689– E696, 1999.—The effects of aand b-2-deoxy-D-glucose tetraacetate (1.7 and 8.5 mM) on insulin, somatostatin, and glucagon secretion from isolated rat pancreases perfused in the pr...

Wiest, Reiner, Vijay Shah, William C. Sessa, and Roberto J. Groszmann. NO overproduction by eNOS precedes hyperdynamic splanchnic circulation in portal hypertensive rats. Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G1043–G1051, 1999.—Chronic high blood flow and the hyperdynamic circulatory syndrome in portal hypertension are associated with endothelial constitutive nitric oxide (NO) ...

Peng, Y., O. W. Moe, T.-S. Chu, P. A. Preisig, M. Yanagisawa, and R. J. Alpern. ETB receptor activation leads to activation and phosphorylation of NHE3. Am. J. Physiol. 276 (Cell Physiol. 45): C938–C945, 1999.—In OKP cells expressing ETB endothelin receptors, activation of Na1/H1 antiporter activity by endothelin-1 (ET-1) was resistant to low concentrations of ethylisopropyl amiloride, indicati...

J. M. ANDREWS,1 H. NATHAN,2 C. H. MALBERT,3 M. A. M. T. VERHAGEN,4 M. GABB,5 G. S. HEBBARD,1 D. KILPATRICK,6 S. MACDONALD,2 C. K. RAYNER,1 S. DORAN,1 T. OMARI,7 E. O’YOUNG,2 C. FRISBY,2 R. J. FRASER,1 M. SCHOEMAN,2 M. HOROWITZ,1 AND J. DENT2 Departments of 1Medicine, 2Gastrointestinal Medicine, and 5Radiology, Royal Adelaide Hospital, and 7Department of Gastroenterology, Women’s and Children’s ...

Simmons, James G., Jolanta B. Pucilowska, and P. Kay Lund. Autocrine and paracrine actions of intestinal fibroblast-derived insulin-like growth factors. Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G817–G827, 1999.— Paracrine and autocrine actions of the insulin-like growth factors (IGFs) are inferred by local expression within the bowel. CCD-18Co cells, IEC-6 cells, and immunoneutral...