The objective of this study was to investigate the antiulcer activity of leaves of Aspilia africana C.D. Adams (Compositae) in rats. Fresh dried leaves of A. africana were extracted by hot water maceration and the yield freeze dried. Antiulcer effects of the aqueous extract at 25, 50 and 100 mg/kg were evaluated in rats using ethanol, indomethacin and aspirin induced ulcer methods. Phytochemica...

The present study was designed to investigate the antiulcer activity of ethyl acetate extract of Citrus decumana (grapefruit) peels. The antiulcerogenic activity was evaluated in water immersion and hypothermic restraint stress models at different doses (150, 250 and 350 mg/kg). The antiulcer potential of the extract was assessed by determining and comparing the ulcerative index and biochemical...

Ficus religiosa is being used in Ayurvedic and Malay traditional medicine for the treatment of various diseases including gastric ulcer. Considering the above claims, the present work was undertaken to validate the anti-ulcer potential of the ethanol extract of leaves of Ficus religiosa against in vivo aspirin induced ulcer and pylorus ligation assays. Gastric ulcers induced in Swiss albino rat...

Ethnobotanical claims regarding Kigelia africana reported antiulcer properties as part of its medicinal application. In this work, aqueous leaf extract from K. africana was investigated for its phytochemical constituents and antiulcer potential against ethanol-induced ulcer in rats. The participation of oxidative stress on ethanol-induced ulcer and the potential protective antioxidant activity ...

BACKGROUND Hazelnut allergy can be a consequence of sensitization to cross-reactive pollen, especially from the Fagales family. However, severe allergic reactions after ingestion of hazelnuts without associated pollen allergy have been reported. In these cases, oral sensitization by hazelnut ingestion is plausible. OBJECTIVE We have reported that antiulcer drugs promote oral sensitization to ...

Direct gastric mucosal cell damage mediated by nonsteroidal anti-inflammatory drugs (NSAIDs) is involved in the formation of NSAID-induced gastric lesions. We recently suggested that this direct cytotoxicity of NSAIDs is caused by their membrane-permeabilization activity. Geranylgeranylacetone (GGA), a clinically used antiulcer drug, can protect gastric mucosa against lesion formation mediated ...