نتایج جستجو برای: antituberculosis
تعداد نتایج: 1869 فیلتر نتایج به سال:
We presented a case of unusual endobronchial inflammatory polyps as a complication following endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in a patient with tuberculous lymphadenitis. EBUS-TBNA of the right hilar lymph node was performed in a 29-year-old, previously healthy man. The patient was confirmed with tuberculous lymphadenitis and received antituberculosis...
Primary adernal insufficiency, the so-called Addision’d disease rarely and few cases have been reported due to tuberculosis. The case, a 55 years old man , complaining of severe malaise & anorexia, was admitted in 22 sept,1996. One week before admission, antituberculosis therapy had been started with a previous diagnosis of cervical lymphadenitis documented by pathologic examination of ...
A total of 43 episodes of tuberculosis lymphadenitis were treated in 32 adult patients. In 12 instances the affected lymph node was excised without any chemotherapy; there were 10 relapses. The treatment was local excision of the affected lymph nodes together with antituberculosis chemotherapy with at least two drugs in 30 instances; there were no relapses following such therapy.Presumably pati...
Benzothiazinones (BTZs) are antituberculosis drug candidates with nanomolar bactericidal activity against tubercle bacilli. Here we demonstrate that BTZs are suicide substrates of the FAD-dependent decaprenylphosphoryl-β-D-ribofuranose 2'-oxidase DprE1, an enzyme involved in cell-wall biogenesis. BTZs are reduced by DprE1 to an electrophile, which then reacts in a near-quantitative manner with ...
Tuberculosis is an opportunistic infection with high morbidity and mortality in solid organ transplant patients. The reasons for this high morbidity and mortality lie mostly in diagnostic difficulties, which cause delays in starting treatment, and associated pharmaceutical toxicity. There are still major issues and difficulties in managing tuberculosis in solid organ transplant patients. These ...
It has been reported that hypereosinophilic syndrome may be induced by antituberculosis drugs. We herein report the case of a 43-year-old man who had been on antituberculosis drugs for two months to treat tuberculous meningitis. During therapy, he suffered from drug rash with eosinophilia and systemic symptoms (DRESS) presenting as acute eosinophilic myocarditis, as confirmed on a histopatholog...
A 61-year-old man was admitted a confirmed COVID-19 with comorbid pulmonary tuberculosis and type 2 diabetes mellitus. The patient given favipiravir therapy, category 1 of antituberculosis drug, insulin therapy. responded well to therapy improved clinical laboratory indicators.
 Key words: COVID-19, tuberculosis, mellitus
Two new series of 2′-hydroxy-retro-chalcone derivatives have been synthesized and fully characterized by IR, 1H NMR, 13C NMR, and mass spectral data. All of these derivatives were evaluated for their antituberculosis activity against Mycobacterium tuberculosis H37Rv. Eight of the tested compounds inhibited the growth of the mycobacterial strain. Among them, compound (E)-1-[4-(decyloxy)phenyl]-3...
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