Aluminium (Al) is the third most abundant element in the earth's crust and its compounds are used in the form of house hold utensils, medicines and in antiperspirant etc. Increasing number of evidences suggest the involvement of Al+3 ions in a variety of neurodegenerative disorders including Alzheimer's disease. Here, we have attempted to investigate the role of Al in endoplasmic reticulum stre...

BACKGROUND Modified Erxian decoction (MEXD), i.e., Erxian decoction (EXD) with Fructus Schisandrae chinensis (Wu Wei Zi) added, has been used to alleviate menopausal symptoms. This study aimed to investigate the effects of MEXD on menopausal sweating and serum hormone levels in a rat model of menopause after oral administration of MEXD. METHODS Quality control of MEXD was conducted by employi...

Sweating is a normal and important mechanism of thermoregulation which is essential for survival. When sweating becomes excessive, the resulting condition is called hyperhidrosis. While hyperhidrosis is not a fatal condition, it can greatly affect one’s quality of life due to its psychological and social impact. To understand this condition, it is necessary to explore the biology of sweat gland...

Astragaloside IV (AGS-IV) is a main active ingredient of Astragalus membranaceus Bunge, a medicinal herb prescribed as an immunostimulant, hepatoprotective, antiperspirant, a diuretic or a tonic as documented in Chinese Materia Medica. In the present study, we employed a high-throughput comparative proteomic approach based on 2D-nano-LC-MS/MS to investigate the possible mechanism of action invo...

Primary Hyperhidrosis (PHH) is a disease of genetic origin, characterized by excessive secretion of eccrine sweat, mainly within palms, armpits and feet (1, 2, 3). Having onset in early childhood or adolescence, according to correspondence research the disease concerns circa 0.6-1% of the Caucasian population (4, 5) and is associated with significant reduction of life quality resulting from imp...

An Bras Dermatol. 2017;92(6):891-900. The FS or auriculotemporal syndrome or gustatory sweating results from the salivary stimulus during and immediately after eating, seeing, thinking about, or talking about certain foods. 2,3 The hypothesis is that, after a parotid gland trauma, a lesion would occur to the auriculotemporal branch of the trigeminal nerve, followed by an anomalous and aberrant ...

Sportswear worn next to the skin is easily soaked by sweat and may become a breeding ground for microbiome, thus source of malodor. Malodor can cause social embarrassment discomfort both wearer others. Given risks current deodorant products pose nature human life, development sustainable textiles odor control comes forefront. This review introduces odor-generating mechanism in clothing from per...

The retention, distribution, metabolism, and excretion of [C]octamethylcyclotetrasiloxane (D4) were studied in Fischer 344 rats after single and multiple exposures to 7, 70, or 700 ppm [C]D4. Subset groups were established for body burden, distribution, and elimination. Retention of inhaled D4 was relatively low (5–6% of inhaled D4). Radioactivity derived from [ C]D4 inhalation was widely distr...

The retention, distribution, metabolism, and excretion of [C]octamethylcyclotetrasiloxane (D4) were studied in Fischer 344 rats after single and multiple exposures to 7, 70, or 700 ppm [C]D4. Subset groups were established for body burden, distribution, and elimination. Retention of inhaled D4 was relatively low (5–6% of inhaled D4). Radioactivity derived from [ C]D4 inhalation was widely distr...