Peyronie's disease (PD) is a connective tissue disorder involving the tunica albuginea of the corpora cavernosa of the penis. We have published several studies describing a "combined therapy" for PD patients, but the present study aims to clearly demonstrate how the association between various antioxidants in PD treatment can significantly increase the likelihood of therapeutic success. We used...

The significance of dietary antioxidants may be limited by the ability of animals to exploit them. However, past studies have focused on the effects of dietary antioxidants after 'antioxidant forced-feeding', and have overlooked spontaneous antioxidant intake. Here, we found that reproducing female Bicyclus anynana butterflies had higher antioxidant defences and enhanced fecundity when forced t...

Antioxidants are used on a very large scale to try to obtain and preserve optimal health. Nutraceuticals and food supplements frequently contain huge dosages of antioxidants. It is not generally recognised that high intake of antioxidants may also have adverse effects. Three antioxidants i.e. vitamin E, β-carotene and lipoic acid are used to illustrate general considerations on the toxicity of ...

BACKGROUND Oxidative stress is the first step involved in mutagenesis, carcinogenesis and aging. There has been great interest in recent years in potentially health benefits of dietary and antioxidant supplements in cancer prevention. OBJECTIVES Our primary objectives were to estimate the global effect of antioxidants on colorectal cancer incidence, adenomatous polyp recurrence, overall morta...

introduction : recurrent aphthous stomatitis (ras) is a common disease with unknown etiology and no treatment. the purpose of this study is to assess the relationship between serum antioxidants level and clinical manifestation. change in antioxidant level can lead inflammatory reaction through oxidative stress. materials & methods : a total 50 patients were selected for this cross sectional stu...

In a structure analysis of the compounds of the genus Piper (Family Piperaceae), we identified five phenolic amides from Piper nigrum, seven compounds from P. retrofractum, and two compounds from P. baccatum. All the phenolic amides possess significant antioxidant activities that are more effective than the naturally occurring antioxidant, alpha-tocopherol. One amide, feruperine, has antioxidan...

This paper reports a methodology for fast analysis of two important antioxidants: tyrosol and oleuropein in real samples of alimentary oils by using a ready-to-use portable microfluidic system (MicruX ® iHVStat) based on microchips electrophoresis with electrochemical detection. The portable system integrates for the first time a high voltage power supply and a bipotentiostat for using microflu...

Antioxidants and Endothelial Dysfunction in Young and Elderly People: Is Flow-Mediated Dilation Useful to Assess Acute Effects? To the Editor: Wray et al reported that acute consumption of antioxidants by healthy subjects had diametrically different effects: flow-mediated dilation increased in elderly people but decreased in young people. The opposite effects are difficult to interpret and reco...

An improved HPLC method is reported for the determination of rosemary's principal phenolic antioxidants, rosmarinic and carnosic acids, providing a fast and simultaneous determination for both of them by using a solid phase column. The analysis was performed with fresh methanolic extractions of Rosmarinus officinalis. To quantify the amount of antioxidants in a fast and reproducible way by mean...