نتایج جستجو برای: antioxidant function
تعداد نتایج: 1298492 فیلتر نتایج به سال:
It is debated whether exercise-induced ROS production is obligatory to cause adaptive response. It is also claimed that antioxidant treatment could eliminate the adaptive response, which appears to be systemic and reportedly reduces the incidence of a wide range of diseases. Here we suggest that if the antioxidant treatment occurs before the physiological function-ROS dose-response curve reache...
abstract: in this thesis, we focus to class of convex optimization problem whose objective function is given as a linear function and a convex function of a linear transformation of the decision variables and whose feasible region is a polytope. we show that there exists an optimal solution to this class of problems on a face of the constraint polytope of feasible region. based on this, we dev...
Proinsulin misfolding in the endoplasmic reticulum (ER) initiates a cell death response, although the mechanism(s) remains unknown. To provide insight into how protein misfolding may cause β-cell failure, we analyzed mice with the deletion of P58(IPK)/DnajC3, an ER luminal co-chaperone. P58(IPK-/-) mice become diabetic as a result of decreased β-cell function and mass accompanied by induction o...
Physical activities are associated with increased production of reactive oxygen species. The production of reactive oxygen species is dependent of the intensity, duration and type of activity. Although the physiological amounts of reactive oxygen species are necessary to regulate cell reactions, their excessive production can cause numerous damages to the structure and function of cells and wea...
The renal dopaminergic system plays a significant role in controlling sodium excretion and blood pressure (BP). Overwhelming evidence shows that oxidative stress downregulates renal dopamine receptors (D1R), and antioxidant supplementation protects D1R function. However, the mechanisms for benefits of antioxidants in protecting D1R function are unknown. We investigated the role of nuclear facto...
Antioxidant supplements are widely consumed by the general public; however, their effects of on exercise performance are controversial. The aim of this study was to examine the effects of an antioxidant cocktail (α-lipoic acid, vitamin E and coenzyme Q10) on exercise performance, muscle function and training adaptations in mice. C57Bl/J6 mice were placed on antioxidant supplement or placebo-con...
Oxidative stress due to an overwhelming release of reactive nitrogen / oxygen species (R(N)OS) is held largely responsible for sepsis-induced organ failure and mortality. Excessive R(N)OS production is neutralized by endogenous antioxidants (reduced glutathione (GSH), enzymes such as GSH peroxidase, and antioxidant vitamins) but this antioxidant potential becomes dramatically reduced in sepsis....
introduction: perepubertal varicocele can result in hypotrophy of testes, sperm damage and decrease the function of leydig cells in future. pathophysiology of varicocele is unclear. increased reactive oxygen species (ros) is a major theory. there are many controversies in treatment of pediatric varicocele. flaxseed (fs) is the richest source of lignans with antioxidant properties. the aim of th...
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