Actinomycin D, cycloheximide, puromycin and ouabain facilitated the detachment of Ehrlich ascites tumour cells from glass surfaces. The results suggest that the altered detachment pattern is due to impaired synthesis of constituents of the cell periphery, which results in a decrease in its mechanical strength. These reagents have been shown by others to reduce the rate of cell aggregation in va...

SUMMARY BACKGROUND The effectiveness of trabeculectomy in the management of glaucoma is well known. It is the most common intervention for most glaucoma cases treated in the Upper East region. In this region trabeculectomies are, however, performed without adjunctive antimetabolites. OBJECTIVE To report on the outcome of trabeculectomy without adjunctive antimetabolites in controlling the int...

The signs of bleb failure include sub conjunctival cyst disappearance, increased vascularity, decreasing area of bleb and elevated intraocular pressure (IOP) [6]. Those patients at high risk of bleb failure are Africans, with previous ocular inflammation, prolonged topical medication (miotics and sympathomimetics) and aphakia. As there were a great tendency to subconjunctival, episcleral and sc...