نتایج جستجو برای: anticholinesterase
تعداد نتایج: 749 فیلتر نتایج به سال:
The potential anticholinesterase characteristics of some thiazole derivatives (2a–2j), including the 5-nitrothiophene moiety, were examined in this work. 1H-NMR, 13C-NMR, and HRMS spectral data used to determine structure compounds. Using a modified Ellman's spectrophotometric approach, each compound was tested for its ability inhibit acetylcholinesterase (AChE) butyrylcholinesterase (BuChE) en...
Organophosphorus and carbamate insecticides are toxic to insects and mammals by virtue of their ability to inactivate the enzyme acetylcholinesterase. This review addresses the mechanism of inhibition of acetylcholinesterase by organophosphorus and carbamate esters, focusing on structural requirements necessary for anticholinesterase activity. The inhibition of acetylcholinesterase by these com...
A series of E-4-(3-oxo-3-(substituted)prop-1-en-1-yl)benzoic acid derivatives (1-5) were synthesized by the Claisen-Schmidt condensation various ketones with 4-formylbenzoic acid. The anticholinesterase (AChE and BChE), tyrosinase, urease inhibition activities compounds examined. It was found that most active compound against AChE enzyme in activity 1. Compound 4 tyrosinase activity, while 3 ps...
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