نتایج جستجو برای: anticholinergic syndrome

تعداد نتایج: 623855  

Journal: :Journal of the American Medical Directors Association 2009
Ann Kolanowski Donna M Fick Judy Campbell Mark Litaker Malaz Boustani

OBJECTIVES (1) To describe the anticholinergic burden experienced by nursing home residents with dementia using the Anticholinergic Cognitive Burden (ACB) Scale; and (2) to determine the association of anticholinergic burden and engagement in activity. DESIGN Cross-sectional, using baseline data from an ongoing clinical trial. SETTING Nine nursing homes in Pennsylvania. PARTICIPANTS Eight...

Journal: :British medical journal 1971
R C Hughes J G Polgar D Weightman J N Walton

The results are reported of a trial in which 34 patients receiving a stable dose of levodopa for the treatment of idiopathic Parkinsonism, as well as anticholinergic drugs which they had been taking before the introduction of levodopa, underwent withdrawal of their anticholinergic remedies. Withdrawal was gradual over four weeks in 17 patients (group 1) and abrupt in the remaining 17 (group 2)....

Journal: :Journal of neurology, neurosurgery, and psychiatry 1982
Y de Smet M Ruberg M Serdaru B Dubois F Lhermitte Y Agid

Among a population of 75 hospitalised Parkinsonian subjects, confusional states were observed in 46% of demented patients not receiving anticholinergic drugs and in 93% of demented patients under anticholinergic therapy. The sensitivity of demented Parkinsonians to anticholinergic drugs can be attributed to a cholinergic deficiency which has been detected in the cortex and hippocampus of Parkin...

Journal: :Palliative medicine 2014
Kristin M Zimmerman Marci Salow L Michal Skarf Tia Kostas Allison Paquin Mark J Simone James Rudolph

BACKGROUND Delirium may complicate the hospital course and adversely impact remaining quality of life for palliative care inpatients. Medications with anticholinergic properties have been linked to delirium within elderly populations via serum anticholinergic assays. AIM The aim of this study is to determine whether increasing anticholinergic burden, as measured using a clinical assessment to...

2017
Barbara Pfistermeister Thomas Tümena Karl-Günter Gaßmann Renke Maas Martin F. Fromm

PURPOSE Previous studies suggest an association between use of anticholinergic drugs in elderly patients and cognitive impairment. However, there are still limited data on the association of anticholinergic drug use and cognitive impairment as well as contribution of individual drugs to anticholinergic load using large, well-documented patient cohorts treated in geriatric units from Europe. M...

Journal: :International journal of geriatric psychiatry 2013
Yu-Tao Xiang Faith Dickerson Julie Kreyenbuhl Gabor S Ungvari Chuan-Yue Wang Tian-Mei Si Edwin H M Lee Helen F K Chiu Kelly Y C Lai Yan-Ling He Shu-Yu Yang Mian-Yoon Chong Chay-Hoon Tan Ee-Heok Kua Senta Fujii Kang Sim Michael K H Yong Jitendra K Trivedi Eun-Kee Chung Pichet Udomratn Kok-Yoon Chee Norman Sartorius Naotaka Shinfuku

OBJECTIVE This study surveyed the use of anticholinergic medications (ACMs) in older Asian patients with schizophrenia and examined its demographic and clinical correlates. METHOD A total of 1452 hospitalized patients with schizophrenia aged 55 years or older in nine Asian countries and territories were surveyed between 2001 and 2009. The cross-sectional data of patients' socio-demographic an...

Journal: :Age and ageing 2015
Phyo Kyaw Myint Chris Fox Chun Shing Kwok Robert N Luben Nicholas J Wareham Kay-Tee Khaw

BACKGROUND Studies have raised concerns that medications with anticholinergic property have potential adverse effects on health outcomes. OBJECTIVES The objective of this study is to examine the prospective relationships between total anticholinergic burden (ACB) from medications and mortality, and cardiovascular disease (CVD) in a general population. DESIGN Observational study. SETTING C...

Journal: :British Journal of Psychiatry 1984

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