Objective: Intravascular catheter-associated infection has been increasing hospitalization in post-surgery patients mainly due to microbial colonization of the catheter surface and formation of a superficial biofilm layer. The present study is aimed in developing an effective antibacterial device which can prevent colonization of organisms by modification of catheter. Methods: In the present st...

introduction: currently, developing new antibacterial drugs as alternative antibiotics is a very active area of research, due to widspreading widespread prevalence of resistant strains of microorganisms. this work intends to investigate of antibacterial properties and influence on immune blood cells of the silver-based compound hexamethylenetetramine (methenamine) silver nitrate with general fo...

Background: Despite the discovery of numerous antibiotics, drug resistance still remains as a major problem. Therefore, it is important to introduce and replace new sources of drug such as medicinal plants with antimicrobial properties. Objective: The genus Clematis (Ranunculaceae family) has six species in Iran. Aerial parts of Clematis have been used to cure fever and chronic diseases such a...

OBJECTIVE To investigate in children the association between antibacterial drugs and subsequent diagnosis of methicillin-resistant Staphylococcus aureus (MRSA) in the community. DESIGN Population-based case-control study in children 1 to 19 years of age. SETTING Primary care, General Practice Research Database, United Kingdom, 1994-2007. PARTICIPANTS Cases were children who had MRSA diagn...

inhalation delivery of aerosolized antibacterials is preferred over conventional methods of delivery for targeting lung infection. the present study is concerned with the development and characterization of a novel, spray dried, aerosolized, chitosan polyelectrolyte complex (pec) based microparticles containing antibacterials for the treatment of lung infections.chitosan polyelectrolyte complex...

Here we report synthesis of silver nanoparticles using leaf extracts of four varieties of lemongrass (Cymbopogon flexuosus) namely krishna, neema, pragati and suvarna and their antibacterial activities against drug resistant bacteria Staphylococcus aureus, Pseudomonas aeruginosa and Acinatobacter bamunnii. Silver nanoparticles were synthesized by the bio-reduction of silver nitrate solution (1 ...

A series of new 2,4,6-trisubstituted-s-triazine was synthesized, assessed for antimicrobial activity, and characterized by FTIR, (1)HNMR, (13)CNMR, and elemental analysis. The tested compounds, 4d, 4g, 4h, 4k, and 4n, have shown considerable in vitro antibacterial efficacy with reference to the standard drug ciprofloxacin (MIC 3.125 μgmL(-1) against B. subtilis, E. coli, and K. pneumoniae). It ...