134 P&T® • March 2008 • Vol. 33 No. 3 INTRODUCTION Carbapenems represent a class of beta-lactam antibacterial agents with a broad spectrum of activity against grampositive, gram-negative, and anaerobic bacteria. This class is bactericidal in nature, but it does not cover species of Enterococcus faecium, methicillin-resistant Staphylococcus aureus (MRSA), or Stenotrophomonas maltophilia. Collect...

Bacterial foodborne pathogens are a significant health burden and the recent emergence of pathogenic resistant strains due to the excessive use of antibiotics makes it more difficult to effectively treat infections as a result of contaminated food. Awareness of this impending health crisis has spurred the search for alternative antimicrobials with natural plant antimicrobials being among the mo...

BACKGROUND Periodontitis is an inflammatory disease resulting in the destruction of periodontal tissues. Various treatment modalities have been tried in the form of mechanical therapy and surgical therapy. Antimicrobial agents have been used as a monotherapy and as an adjunct with mechanical debridement. Various plant extracts have been used as antibacterial agents. Pineapple extract (bromelian...

Skin is the body's first defense line against environmental pathogens. However, open skin wounds can interfere with the normal function of the skin and the entry of opportunistic bacteria into the body. Recently, the development of nano-dressing containing green antibiotics has been received much attention around the world. In this study, the essential oil of Citrus sinensis (CSEO) was u...

Introduction: Vaginitis is an inflammatory and infectious disease in human host that involved vaginal mucosa. Increase of resistance to various antibacterial agent has been very significant in three or four recent decades and this important subject reveals the use of new and natural sources such as plants with medical and antimicrobial property for eradication of these infections. Therefore, th...

Honey: This topic has been extensively reviewed by Bogdanov, online article with original references on www.bee-hexagon.net/files/file/fileE/Honey/7HoneyNutrientFunctional.pdf The antibacterial effect of honey, mostly against gram-positive bacteria, both bacteriostatic and bactericidal effects have been reported, against many strains, many of which are pathogenic. Honey glucose oxidase produces...

Yotis, William W. (Loyola University, Chicago, Ill.). Hydrolysis of synthetic esters by the antibacterial agent in serum. J. Bacteriol. 91:488-493. 1966.-An antistaphylococcal serum agent was assayed colorimetrically, manometrically, and titrimetrically for esterase activity. p-Nitrophenol acetate, triacetin, l-lysine methyl and ethyl ester, and norleucine methyl ester were hydrolyzed by the an...

silver-polyaniline (ag-pani) nanocomposites were prepared by in-situ oxidative polymerization of aniline monomer in sodium bis(2-ethylhexyl) sulfosuccinate (aot) solution as an emulsifier. the synthesis of silver-polyaniline nanocomposites was investigated as a function of several parameters such as aniline concentration, concentration of emulsifier (aot), concentration of oxidation agent and c...

This study explored the potential use of new silver abietate obtained from abietic acid as an antibacterial agent for textile applications. Synthesis, structure, and antibacterial studies of silver abietate compound are reported. Silver complex was obtained reacting abietic acid with silver. The new compounds were characterized by (1)H NMR, (13)C NMR, DEPT, IR, UV, and ESI-MS techniques which s...

Protocatechualdehyde (PCA) is an important plant-derived natural product that has been associated with a wide variety of biological activities and has been widely used in medicine as an antioxidant, anti-aging and an anti-inflammatory agent. However, fewer reports concerning its antibacterial effects on plant-pathogenic bacteria exist. Therefore, in this study, protocatechualdehyde was evaluate...