1. Antipneumococcic serum contains in addition to the antibodies against the various bacterial constituents, a non-antibacterial therapeutic factor. 2. The non-antibacterial factor has been separated from the antibacterial antibodies by absorption with homologous, heat-killed, virulent pneumococci. 3. The non-antibacterial factor is not type-specific; it is probably species-specific; it is not ...

neonatal bacterial sepsis is one of the major cause of morbidity and mortality in neonates. this retrospective study was performed to determine the incidence of bacterial sepsis with focus on gram negative organisms in neonates admitted at beheshti hospital in kashan, during a 3-yr period, from september 2002 to september 2005. blood culture was performed on all neonates with risk factors or si...

OBJECTIVES Quinolone resistance in the opportunistic pathogen Pseudomonas aeruginosa is commonly caused by mutations that alter the target molecules DNA gyrase/topoisomerase IV, or cause activation of various efflux systems. We have analysed the effect of quinolone resistance caused by DNA gyrase/topoisomerase IV mutations on bacterial fitness. METHODS Norfloxacin-resistant mutants were isola...

The systemic immune response of Trichoplusia ni after Bacillus thuringiensis (Bt) exposure was evaluated by comparing the expression of genes encoding antimicrobial peptides (AMPs) in Bt-susceptible and -resistant T. ni strains that were either exposed or not to XenTari (Bt-XT). AMP genes were detected by RT-PCR using primers for attacin, gloverin, lebocin, lysozyme, and peptidoglycan recogniti...

BACKGROUND Recent public health efforts, including in the UK and US, have targeted decreasing unnecessary antibiotic use. In the US, prescribing for acute non-specific respiratory infections (ARIs) has decreased, but broad-spectrum antibacterial prescribing has soared. AIM To assess recent trends in antibacterial prescribing for ARIs in the UK. DESIGN OF STUDY Retrospective cohort. SETTIN...

This study evaluated the effect of EDTA and lysozyme on the antibacterial activities of activated ovotransferrin against 5 strains of Listeria monocytogenes. First, a disc test was performed to screen the concentrations of EDTA or lysozyme that showed antibacterial activities in ovotransferrin (O) or ovotransferrin in 100 mM NaHCO3 (OS) solution. Turbidity and viability tests were conducted usi...

Staphylococcus aureus is a Gram-positive bacterium that causes many harmful and life-threatening diseases. Some strains of this bacterium are resistant to available antibiotics. This study was designed to evaluate the ability of indigenous actinomycetes to produce antibacterial compounds against S. aureus and characterize the structure of the resultant antibacterial compounds. Therefore, a slig...

In this study, 2-(N-pyrrolidine-alkyl) tanshinones bearing pyrrolidine groups were synthesized and the antibacterial mechanism was explored. These derivatives selectively elicited antibacterial activity against Gram-positive bacteria. Moreover, their antibacterial activities were time-, concentration-dependent and persistent. It appeared that Fenton-mediated hydroxyl radicals were involved, and...

Antibacterial activity of two cyanobacterial strains i.e. Nostoc polludosum and Cylindrospermum licheniforme was studied. Both cyanobacterial strains were isolated from agricultural fields of Varanasi, India. Crude extracts of both strains in five solvents i.e. Ethanol, Petroleum ether, Acetone, Methanol, and Chloroform were screened against two human pathogenic bacteria i.e. S. aureus and E. c...

The emergence of multidrug-resistant bacteria is a global threat for human society. There exist recorded data that silver was used as an antimicrobial agent by the ancient Greeks and Romans during the 8th century. Silver nanoparticles (AgNPs) are of potential interest because of their effective antibacterial and antiviral activities, with minimal cytotoxic effects on the cells. However, very fe...