Satureja khuzestanica Jamzad (Marzeh Khuzestani in Persian) is an endemic plant that iswidely distributed in the southern part of Iran. Despite the number of papers published on thisplant, no one has focused on its anticancer effects. Therefore, the present study was designedto investigate the selective cytotoxic and anti-proliferative properties of satureja khuzestanicatotal extract (SKE). MCF...

Satureja khuzestanica Jamzad (Marzeh Khuzestani in Persian) is an endemic plant that iswidely distributed in the southern part of Iran. Despite the number of papers published on thisplant, no one has focused on its anticancer effects. Therefore, the present study was designedto investigate the selective cytotoxic and anti-proliferative properties of satureja khuzestanicatotal extract (SKE). MCF...

There are several challenges involved in the development of effective anti-cancer drugs, including accurate drug delivery without toxic side effects. Possible systemic toxicity and the rapid biodegradation of drug carriers are potential risks in the use of carriers for drug-delivery formulations. Therefore, the carrier-free drug delivery of an anti-cancer drug is desirable. Herein, 4-amino-2-be...

Benzimidazole (BMZ) family of anti-worm drugs has been now repurposed as anti-cancer drugs. However, offering a general reformulation method for these is essential due to their hydrophobicity and low aqueous solubility. In this work, we developed approach load typical BMZ tiny nanocrystals within lipid-coated calcium phosphate (LCP) nanoparticles. drug-loaded LCP nanoparticles increased solubil...

Cancer is a major cause of death worldwide, as exemplified by millions cancer diagnoses every year. The use chemotherapy in treating has many disadvantages which include recurrence cancer, associated with drug resistance, and severe side effects that are harmful to the patients. A better source anticancer drugs can come from nature. Strobilanthes crispus (S. crispus) herbal medicinal plant indi...

The up-and-coming microfluidic technology is the most promising platform for designing anti-cancer drugs and new point-of-care diagnostics. Compared to conventional drug screening methods based on Petri dishes animal studies, delivery in systems has many advantages. For instance, these platforms offer high-throughput screening, require a small number of samples, provide an vivo-like microenviro...

background: bleomycin (blm) is an anti-cancer drug widely used in the treatment of cancer. blm causes several side effects related to dna and cellular damage. the aim of this study was investigated the effects of tea polyphenol epicatechin on anti-proliferative effects induced by bleomycin in human normal skin and human ovarian cancer cells.materials and methods: human ovarian cancer cell (skov...