نتایج جستجو برای: anti angiogenic activity

تعداد نتایج: 1430891  

Journal: :Biological & pharmaceutical bulletin 2014
Jun Lee Jin-Mu Yi Haejin Kim You Jin Lee Jong-Shik Park Ok-Sun Bang No Soo Kim

Angiogenesis, the process of new vessel formation from the pre-existing blood vasculature, is critical for continuous tumor growth and is considered to be a validated antitumor target. The results of our previous study demonstrate the anti-angiogenic potential of an extract of Gleditsia sinensis thorns, which has been traditionally used in Korean medicine to remedy diverse diseases, including t...

Journal: :Journal of Investigative Dermatology 2023

Hyaluronan (HA) is a high molecular weight linear glycosaminoglycan and abundant in the skin extracellular matrix. Cutaneous HA first depolymerized to intermediate sizes then further fragmented regional lymph nodes. High anti-inflammatory anti-angiogenic, whereas pro-inflammatory pro-angiogenic. We have reported that HYBID (HA-Binding protein Involved Depolymerization), also known as KIAA1199/C...

Journal: :Haematologica 2015
Flavia C M Lopes Fabiola Traina Camila B Almeida Flavia C Leonardo Carla F Franco-Penteado Vanessa T Garrido Marina P Colella Raquel Soares Sara T Olalla-Saad Fernando F Costa Nicola Conran

As hypoxia-induced inflammatory angiogenesis may contribute to the manifestations of sickle cell disease, we compared the angiogenic molecular profiles of plasma from sickle cell disease individuals and correlated these with in vitro endothelial cell-mediated angiogenesis-stimulating activity and in vivo neovascularization. Bioplex demonstrated that plasma from patients with steady-state sickle...

Journal: :Indian journal of physiology and pharmacology 2011
Rajani Mathur Suresh Kumar Gupta Sandeep Rajinder Mathur Thirumurthy Velpandian

Angiogenesis is controlled by number of growth factors, including vascular endothelial growth factor (VEGF). Plant derived anti-angiogenic molecules acting via VEGF are being investigated for curtailing angiogenesis dependent diseases. In this study, methanolic (CM), n-hexane (CH), ethylacetate (CE) and water (CW) extracts of the roots of Calotropis procera were tested for anti-angiogenic activ...

Journal: :European Journal of Pharmaceutics and Biopharmaceutics 2017

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