A series of N-[3-{(1H-benzo[d]imidazol-2-ylthio) methyl}-5-mercapto-4H-1, 2, 4-triazol-4yl]-2-substituted phenoxy acetamide 6(a-g) were synthesized by the mixture of the compound of potassium 2-(2-(1H-benzo[d]imidazol-2-ylthio) acetyl) hydrazinecarbodithioate (4) and aryloxy acid hydrazide (5) in presence of hydrochloric acid. The predicted structures of the synthesized compounds were confirmed...

This study describes a biological investigations of methanolic extract of Jatropha gossypiifolia, a plant belonging to the family Euphorbiaceae. The aim of this investigation was to expose the viable phytochemical constituents properly as their contribution towards the antioxidant, anthelmintic and membrane stabilizing activities. The anthelmintic test was conducted on earthworm Pheritima phost...

The present work deals with the synthesis of some novel azo derivatives of dihydropyrimidinones. The structures of newly synthesized compounds were established on the basis of their FTIR, 1H NMR, Mass spectrometry and elemental analysis data results. The synthesized agents were assessed for their in vivo anti-inflammatory activity on the Wistar albino rats. The compounds were also screened for ...

A series of novel 1[5"-(2"'-substituted phenyl)-4",5"'-dihydro isoxazole-3"-yl]-3-[(4 substituted phenyl)imino]1-3-dihydro-2H-indole-2-one were synthesized from different substituted chalconised indole-2,3-dione was prepared from the different chalconised Isatin. The structures of the compounds were elucidated by elemental and spectral (IR, (1)H NMR, and MS) analysis. The synthesized compounds ...

Neurocysticercosis (NCC), an infection of the brain with the larval stage of the Taenia solium tapeworm, is responsible for an estimated one-third of adult-onset epilepsy cases in regions of the world where it is endemic. Currently, anthelmintic drugs used for treatment of NCC are only partially effective, and there is, therefore, a pressing need for new therapeutic agents. Discovery of new ant...

Study in uitro on the anticestodal activity of Coleus blu111ei leaves extracts against Hy111e11olepis 111icrosfolll11 was conducted. Leaves of C. blwuci were collected and extracted ·with hexane, chloroform, ethanol and water. Anthelmintic activity was evaluated with an assay using H. 111icrosfolllll in a serial microplate dilution method by determination of mortality time. The parasites were t...