Porokeratosis, a keratinization and fibroblast cutaneous disorder, is a progressive disease with limited treatment options. We describe a case of linear porokeratosis that responded favorably to a series of 585 nm pulsed dye laser treatments. In addition to its vascular specificity, the pulsed dye laser presumably produces a direct effect on collagen, as well as an indirect effect on histamine ...

Eruptive disseminated porokeratosis (EDP) is a disease that presents clinically with sudden onset of erythematous papules and plaques, with a ridge-like border histologically represented by a cornoid lamella. We report a case of EDP occurring in a 39-year-old woman 3 days after completion of a 2-week course of oral corticosteroid therapy for an acute asthma exacerbation. The patient was treated...

Porokeratosis is a disorder of keratinization showing a well-defined lesion with a hyperkeratotic ridge on the border that contains the coronoid lamella. We report familial (autosomal dominant with reduced penetrance) disseminated plaque type (Mibelli's type) porokeratosis in a father and son. In the father, there were multiple horns and a large squamous cell carcinoma in a large lesion over th...

Abstract A 45-year-old man with a history of psoriasis presented to our male genital dermatology clinic several-year pruritic, painful, hyperkeratotic red–brown plaques on both buttocks. He had previously been treated unsuccessfully cryotherapy and topical imiquimod podophyllotoxin for suspected condyloma acuminata. 4-mm punch biopsy from the left buttock showed hyperkeratosis, hypergranulosis,...

Only 6 cases with an association of disseminated superficial porokeratosis with dermal amyloid deposits are reported in the literature. We present the case of a 76-year-old woman who presented with a disseminated superficial porokeratosis. Histological examination revealed amyloid deposits in the upper dermis, which were typed with routine HE stains, Congo red stains and anticytokeratin antibod...