Daily rhythms of physiology and behaviour are governed by an endogenous timekeeping mechanism (a circadian 'clock'), with the alternation of environmental light and darkness synchronizing (entraining) these rhythms to the natural day-night cycle. Our knowledge of the circadian system of animals at the molecular, cellular, tissue and organismal levels is remarkable, and we are beginning to under...

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Proteomics holds significant promise as a method for advancing animal science research. The use of this technology in animal science is still in its infancy. The ability of proteomics to simultaneously identify and quantify potentially thousands of proteins is unparalleled. In this review, we will discuss basic principles of doing a proteomic experiment. In addition, challenges and limitations ...

PRINCIPLES AND METHODS Transgenic Animals and Genetic Research Prior to the current revolution in applied molecular genetics, the only practical method to study the regulation and function of mammalian genes was to utilize spontaneous mutants. To prove the genetic basis of the mutation, the animals had to transmit an observable trait to offspring. Since the 1970s, it has been possible to introd...

Many researchers have studied the oxytetracycline (OTC) pharmacokinetic profile following oral administration in multiple aquatic animal species including shrimp[1-5], sea turtles[6], and fish[7-11], However, Rigos & Smith[12], described the void of data in the literature showing a clinical effect of OTC in fish that could be directly predicted, correlated, or assessed from OTC concentrations i...