Reliable animal models are invaluable for monitoring the extent of pollution in the aquatic environment. In this study, we demonstrated the potential of huORFZ, a novel transgenic zebrafish line that harbors a human upstream open reading frame of the chop gene fused with GFP reporter, as an animal model for monitoring environmental pollutants and stress-related cellular processes. When huORFZ e...

Adelphophagy occurs when encapsulated embryos complete development by feeding on their developing siblings, which are known as nutritive embryos. Nutritive embryos are found in a variety of animal groups, and are especially common in some groups of marine invertebrates. Although they have evolved numerous times independently in the calyptraeid gastropods, adelphophagic development with nutritiv...

Stereoblastic embryos from the Doushantuo Formation of China exhibit occasional asynchronous cell division, with diminishing blastomere volume as cleavage proceeded. Asynchronous cell division is common in modern embryos, implying that sophisticated mechanisms for differential cell division timing and embryonic cell lineage differentiation evolved before 551 million years ago. Subcellular struc...

In 1946 Nelson and Evans (1) reported that pantothenic acid (PaA) deficiency in rats often resulted in the fetal death with resorption, and suggested the importance of vitamins in the development of embryos. Lefebvres-Boisselot (2) observed a high incidence of cerebral and ocular defects, digital hemor rhages and edema in the fetuses from PaA-deficient rats. In 1948 Ackermann and Taylor (3) fir...

Background: Development of cloned bovine embryos. Materials and Methods: Oocytes collection,oocyte denudation, oocyte enucleation, nuclear transfer, electrofusion, reconstructed embryo activation, culture of reconstructed and IVF embryo,and treatment with SAH post fusion interval Treatment of reconstructed embryos with TSA for 12 hours after activation, preparation of somatic donor cells, donor...

To educate its citizens about research into chimeras [3] made from human and non-human animal cells, the United Kingdom's Human Fertilisation Embryology Authority published the consultation piece "Hybrids and Chimeras: A Consultation on the Ethical and Social Implications of Creating Human/Animal Embryos in Research," in 2007. The document provided scientific and legal background, described eth...

In 2007, the Human Fertilisation and Embryology Authority in London, UK, published "Hybrids and Chimeras: A Report on the Findings of the Consultation", which summarized a public debate about research on, and suggested policy for, human animal chimeras [4]. The HFEA formulated the report after conducting a series of surveys and debates from earlier in 2007. The HFEA issued a statement in Septem...

In 2007, the Human Fertilisation and Embryology Authority in London, UK, published "Hybrids and Chimeras: A Report on the Findings of the Consultation", which summarized a public debate about research on, and suggested policy for, human animal chimeras [4]. The HFEA formulated the report after conducting a series of surveys and debates from earlier in 2007. The HFEA issued a statement in Septem...

In 2007, the Human Fertilisation and Embryology Authority in London, UK, published "Hybrids and Chimeras: A Report on the Findings of the Consultation", which summarized a public debate about research on, and suggested policy for, human animal chimeras [4]. The HFEA formulated the report after conducting a series of surveys and debates from earlier in 2007. The HFEA issued a statement in Septem...

Xenopus laevis fertilized eggs have been treated with wheat germ agglutinin (WGA) before the onset of the first cleavage, at the stripe stage and during groove deepening. The ultrastructure of the animal cortex of the arrested embryos has been compared with that of the same region of control embryos at different stages of first furrow formation and of cytochalasin B-treated embryos. The outer s...