Diabetic macular edema (including diabetic retinopathy in persons with macular edema) Macular edema following retinal vein occlusion (RVO) Neovascular (wet) AMD Neovascular glaucoma Pseudoxanthoma elasticum Rare causes of choroidal neovascularization (angioid streaks, choroiditis [including choroiditis secondary to ocular histoplasmosis], idiopathic degenerative myopia, retinal dystrophies, rub...

The ocular fingings in 60 patients with homozygous sickle-cell disease over the age of 40 years have been described. Peripheral retinal vessel disease was common and appeared to increase with age. Retinitis proliferans was common among older patients in the group. Angioid streaks occurred in 13 (22 per cent) patients.

Angioid streaks are commonly related to Grönblad-Strandberg syndrome, that often shows dermatological characteristics, such as pseudoxanthoma elasticum. Choroidal neovascularization is uncommon, often occurring after ocular trauma. This is a case report of the successful use of intravitreal bevacizumab for the treatment of choroidal neovascularization secondary to Grönblad-Strandberg syndrome.

Submit Manuscript | http://medcraveonline.com Abbreviations: IVB: Intravitreal Bevacizumab; CNV: Choroidal Neovascularization; AS: Angioid Streaks; PXE: Pseudoxanthoma Elasticum; FFA: Fundus Fluorescein Angiography; OCT: Optical Coherence Tomography; RPE: Retinal Pigment Epithelium; PDT: Photo Dynamic Therapy; VEGF: Vascular Endothelial Growth Factor; AMD: Age-related Macular Degeneration; BCVA...

PURPOSE To investigate the value of multimodal confocal scanning laser ophthalmoscopy (cSLO) for phenotyping fundus lesions in patients with pseudoxanthoma elasticum (PXE) and to correlate these findings with morphologic alterations detected by spectral domain optical coherence tomography (SD-OCT). METHODS Imaging was performed with a combined SD-OCT-cSLO system (Spectralis HRA-OCT; Heidelber...