Most cell types express several tropomyosin isoforms, the individual functions of which are poorly understood. In rat fibroblasts there are at least six isoforms; TM-1, TM-2, TM-3, TM-4, TM-5a, and TM-5b. TM-1 is the product of the beta gene. TM-4 is produced from the TM-4 gene, and TMs 2, 3, 5a, and 5b are the products of the alpha gene. To begin to study the localization and function of the i...

Objective(s): To illuminate the functional effects of allicin on rats with cognitive deficits induced by tunicamycin (TM) and the molecular mechanism of this process. Materials and Methods: 200–250 g male SD rats were divided into three groups at random: control group (n=12), TM group (5 μl, 50 μM, i.c.v, n=12), and allicin treatment group (180 mg/kg/d with chow diet, n=12). After 16 weeks of a...

background: this study was done to assess the use of traditional/complementary and alternative medicine (tm/cam) during pregnancy and the reasons behind it from the mother’s perspective. materials and methods: in a cross-sectional study, 919 pregnant mothers attending at prenatal care units of governmental health centers recruited through a multistage sampling and completed a self-report questi...

OBJECTIVE Thrombomodulin (TM), a glycoprotein constitutively expressed in the endothelium, is well known for its anticoagulant and anti-inflammatory properties. Paradoxically, we recently found that monocytic membrane-bound TM (ie, endogenous TM expression in monocytes) triggers lipopolysaccharide- and gram-negative bacteria-induced inflammatory responses. However, the significance of membrane-...

BACKGROUND The development of animal models that approximate human frailty is necessary to facilitate etiologic and treatment-focused frailty research. The genetically altered IL-10(tm/tm) mouse does not express the antiinflammatory cytokine interleukin 10 (IL-10) and is, like frail humans, more susceptible to inflammatory pathway activation. We hypothesized that with increasing age, IL-10(tm/t...

Transition-metal (TM) boride and carboride nanostructures are studied as model organometallic materials for hydrogen storage. The dispersed TM atoms function as H2 sorption centers on the surface of the boron or carbon-boron substrate. The flexibility offered in the variety of possible structures permits the study of the effect of the TM-TM distance on the storage capacity. When the TMs are too...

Let p be a polynomial in non-commutative variables x1,x2,…,xn with constant term zero over an algebraically closed field K. The object of study this paper is the image kind algebra upper triangular matrices Tm(K). We introduce family polynomials called multi-index p-inductive for given p. Using we will show that, if identity Tt(K) but not Tt+1(K), then p(Tm(K))⊆Tm(K)(t−1). Equality achieved cas...

OBJECTIVE To compare TVT(TM) , Pelvicol(TM) and autologous fascial slings (AFSs). DESIGN A multicentre randomised control trial. SETTING Four units in the UK. POPULATION Women requiring primary surgery for stress urinary incontinence (SUI). METHODS A total of 201 women with urodynamically proven stress incontinence were randomised into three groups and assessed at baseline, 6 weeks, 6 m...