نتایج جستجو برای: anaplastic lymphoma

تعداد نتایج: 111991  

2016
Chen Tian Yizhuo Zhang

INTRODUCTION Most primary stomach lymphomas are now recognized to originate from B-cell. Primary gastric anaplastic lymphoma kinase (ALK)-negative anaplastic large-cell lymphoma (ALCL) as shown in this case is very rare. CASE REPORT A 59-year-old man presented with a 1-month history of epigastric pain. Computed tomography showed a tumor in the stomach with perigastric lymphadenopathy. Biopsy ...

2013
Rowan L. Grigoropoulos Penny Wright Mars B. van t'Veer Mike A. Scott George A. Follows

Anaplastic large cell lymphoma with a small cell pattern is a rare T-cell lymphoma. This condition is more frequently seen in younger patients and should be considered when patients present with leucocytosis and constitutional symptoms. In this report, we describe our diagnostic work-up for one such case using blood, lymph node, and bone marrow aspirate samples, highlighting the variability of ...

2016
Jeong Eun Kim Eui Hyun Oh Young Suck Ro Joo Yeon Ko

Anaplastic large-cell lymphoma (ALCL) is a CD30-positive T-cell/null-cell lymphoma that is clinically classified into either primary cutaneous ALCL or systemic ALCL (S-ALCL) sub-types. Because 90% of childhood S-ALCL cases are anaplastic lymphoma kinase (ALK)-positive, there is a lack of data on ALK-negative S-ALCL cases among pediatric patients. Herein, we report a rare case of ALK-negative S-...

1999
Brunangelo Falini Stefano Pileri Pier Luigi Zinzani Antonino Carbone Vittorina Zagonel Chris Wolf-Peeters Gregor Verhoef Fabio Menestrina Giuseppe Todeschini Marco Paulli Mario Lazzarino Roberto Giardini Antonella Aiello Hans-Dieter Foss Iguacyra Araujo Marco Fizzotti Pier-Giuseppe Pelicci Leonardo Flenghi Massimo F. Martelli Antonella Santucci

A distinct pathologic entity (ALK1 lymphoma) that is characterized by expression of the anaplastic lymphoma kinase (ALK) protein has recently emerged within the heterogeneous group of CD301 anaplastic large-cell lymphomas. Information on clinical findings and treatment outcome of ALK1 lymphoma is still limited, and no data are available concerning the value of the International Prognostic Index...

2005
Hun Ho Song Gwang Ho Baik Jung Hye Kwon Keun Seok Lee Young Hee Choi Kyung Chan Choi Young Eui Park

Gastric CD30-positive anaplastic large-cell lymphoma is a very rare disease. It is sometimes difficult to distinguish it from undifferentiated carcinoma, sarcoma and so on. We report here on a case of primary gastric anaplastic large-cell lymphoma. A 50-yr-old woman complained of epigastric pain and severe chest pain for 1 week. The gastroendoscopic examination revealed geographic mucosal irreg...

Journal: :International journal of clinical and experimental pathology 2009
Shiyong Li

Anaplastic lymphoma kinase-positive large B-cell lymphoma (ALK(+) LBCL) represents a distinct subtype of mature B-cell neoplasms in the most recent WHO classification of hematolymphoid neoplasms. It has a characteristic immunoblastic/plasmablastic morphology, a distinct immunophenotypic profile and recurrent cytogenetic/molecular genetic abnormalities, and has been reported in both the adult an...

Journal: :Acta otorrinolaringologica espanola 2013
Verónica Rodríguez José María Perolada Isabel Ibañez Amets Fernández

Anaplastic large T-cell lymphoma is a very rare disease in childhood. The most common locations are lymph nodes and skin, while the external ear location is uncommon. We present the case of a 6-year-old child with an earlobe tumour. Surgical treatment was performed and the anatomopathological results showed anaplastic large cell lymphoma. Radiological tests were negative and there was no system...

Journal: :Archives of ophthalmology 1999
E Tanzi M Edelman P S Rosenbaum

Ki-1-positive anaplastic large-cell lymphoma is an uncommon form of non-Hodgkin lymphoma. It lies within a spectrum of recently identified lymphoproliferative disorders. The entities within this spectrum share similar clinical and histopathologic characteristics that can make the diagnosis challenging. We report a case of Ki-1-positive anaplastic large-cell lymphoma involving the right upper ey...

2016
Kozo Nagai Yukari Suyama Daisuke Koga Masanori Nishi Chiaki Iida Katsuya Tashiro Atsushi Danjo Keita Kai Muneaki Matsuo

We described an 11-year-old boy suffering from pediatric anaplastic lymphoma kinase-positive anaplastic large cell lymphoma with heart metastasis at diagnosis and arterial tumor embolisms during chemotherapy. Both the heart metastasis and pericardial effusion showed improvement with prednisolone, but numbness and pallor sequentially developed in his lower extremities during the first course of ...

Journal: :Hematology/oncology and stem cell therapy 2011
K Khodadad S Karimi M Arab Z Esfahani-Monfared

Primary anaplastic large cell lymphoma of the trachea is a rare tumor. Common complaints are dyspnea and cough that could mimic a partially refractory asthma in some cases. We report a 16-year-old female with an anaplastic large cell lymphoma (null cell type) in which tracheal involvement was presented with life-threatening airway obstruction and subcutaneous emphysema. After debulking the tumo...

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