نتایج جستجو برای: analgesic and antipyretic
تعداد نتایج: 16829709 فیلتر نتایج به سال:
Paracetamol is a commonly used NSAID (Non-steroidal anti-inflammatory agent) since its introduction by Von Mering in 1893. Its popularity is because of its long safety record and good efficacy in children and adults. Though it has been used for so many years, its mechanism of action is yet to be elucidated. NSAIDS inhibit prostaglandin synthesis by inhibiting COX-1(Cyclooxygenase-1) and COX-2(C...
BACKGROUND Acetaminophen (APAP) is a commonly used analgesic and antipyretic. When administered in high doses, APAP is a clinical problem in the US and Europe, often resulting in severe liver injury and potentially acute liver failure. Studies have demonstrated that antioxidants and anti-inflammatory agents effectively protect against the acute hepatotoxicity induced by APAP overdose. METHODS...
The leaves of Acalypha wilkesiana are commonly used for the treatment of pain, fever and ulcer by traditional medical practitioners without any scientific data to evaluate the appropriateness of some of the practices. Therefore, this study was carried out to determine whether the ethanol extract of Acalypha wilkesiana has analgesic, anti-inflammatory and antipyretic as well as anti-ulcer effect...
Paracetamol also known as acetaminophen, is a widely used analgesic and antipyretic agent. We report the synthesis and biological evaluation of adamantyl analogues of paracetamol with important analgesic properties. The mechanism of nociception of compound 6a/b, an analog of paracetamol, is not exerted through direct interaction with cannabinoid receptors, nor by inhibiting COX. It behaves as a...
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