Introduction:Radiotherapy (RT) plays an important role in treatment of head and neck cancers. In almost 75% of patients with head and neck cancers, RT as the main treatment method is used in order to radical or palliative treatment. Hearing loss is one of the side effects of RT for patients whose inner ear is included in radiation field. The aim of this study was to evaluate th...

background: bordetella pertussis is the causative agent of pertussis. in brazil, laboratory diagnosis of pertussis is based on the culture. in 2010, was standardized the real-time pcr taqman® in routine diagnosis. objectives: the aim of this study was to evaluate the impact achieved with the introduction of rt-pcr for the routine diagnosis of pertussis and to compare with the results obtained f...

seeds of the castor bean plant ricinuscommunis l (cb) contain ricin toxin (rt), one of the most poisonous naturally-occurring substances known. ricin toxin, a water-soluble glycoprotein that does not partition into the oil extract, is a ribosome-inactivating toxin composed of two chains, labeled a and b. severity of the toxicity varies depending on the route of exposure to the toxin. inhalation...

Background: To investigate the expression of TNF-α, IL-6, IL-10 in the plasma of patients with lung cancer who received radiation therapy (RT), and to analyze the correlation between these cytokines and radiation pneumonitis (RP). Materials and Methods: Patients with lung cancer who received 3D-CRT in our hospital were prospectively evaluated. Circulating cytokine levels were measured wit...

Rapid antigen and antibody, serological tests, and RT ‑ PCR-based molecular methods are widely used for the detection of microorganisms worldwide. Objectives: This study aimed by Isothermal nucleic acid amplification techniques to detect the covid-19. Methods: In this study, 200 samples of nasopharynx and oropharynx were collected from Jamaran Heart Hospital in Tehran. Covid -19 was exami...

We read with great interest the Highlight Review by Dr C GruÈ ndker entitled `Cytotoxic luteinizing hormonereleasing hormone conjugates and their use in gynecological cancer therapy' in the European Journal of Endocrinology (1). This excellent article provides a detailed description of recent developments in the field of targeted chemotherapy based on luteinizing hormone-releasing hormone (LH-R...

MicroRNA (miRNA) detection by reverse transcription (RT) quantitative real-time PCR (RT-qPCR) is the most popular method currently used to measure miRNA expression. Although the majority of miRNA families are constituted of several 3'-end length variants ("isomiRs"), little attention has been paid to their differential detection by RT-qPCR. However, recent evidence indicates that 3'-end miRNA i...

Several technologies, such as electromagnetic midsagittal articulography (EMA) or real-time magnetic resonance (RTMRI), enable studying the static and dynamic aspects of speech production. The resulting knowledge can, in turn, inform the improvement of speech production models, e.g., for articulatory speech synthesis, by enabling the identification of which articulators and gestures are involve...