Modeling side-chain conformations on a fixed protein backbone has a wide application in structure prediction and molecular design. Each effort in this field requires decisions about a rotamer set, scoring function, and search strategy. We have developed a new and simple scoring function, which operates on side-chain rotamers and consists of the following energy terms: contact surface, volume ov...

Sound pressure levels in facilities that house acoustically sensitive animals should be monitored on a regular basis as a standard component of animal care. Monitoring of noise levels in the pools housing Lagenorhynchus obliquidens (Pacific white-sided dolphins) at the Vancouver Aquarium during regular operations revealed average sound pressure levels (SPLs) across all frequency bins of 91.9 (r...

This study evaluated the mechanical accuracy of an in-house-developed couch-based tracking system (CBTS) according to respiration data. The overall delay time of the CBTS was calculated, and the accuracy, reproducibility, and loading effect of the CBTS were evaluated according to the sinusoidal waveform and various respiratory motion data of real patients with and without a volunteer weighing 7...

The aim of this study was to provide detailed information on rationales, calculations, and results of common methods used to quantify reproducibility in plantar pressure variables. Recreational runners (N=95) performed multiple barefoot running trials in a laboratory setup, and pressure variables were analyzed in nine distinct subareas of the foot. Reproducibility was assessed by calculating in...

In this paper we present a characterization of those Wiener functionals that are the likelihood ratio for a 'signal plus independent noise' model. The characterization is expressed in terms of the representation of such functionals in a series of multiple Wiener integrals. Let {ys, 0 <s =z r} be a random process with measurable sample functions satisfying ] y, ] G K as. Let { Ws, 0 <s < T} be a...

PURPOSE To examine the variability of saccadic peak-velocity amplitude relationships in myasthenic and nonmyasthenic ocular palsies. METHODS The authors measured centrifugal saccades in nine patients with myasthenia gravis, nine patients with proven nonmyasthenic ocular palsies, and three normal subjects. Patients made repetitive saccades for 8 minutes. Saccades were analyzed at the start of ...

This study determines whether maximal voluntary ankle plantar flexor torque could be more accurately represented using a torque generator that is a function of both knee and ankle kinematics. Isovelocity and isometric ankle plantar flexor torques were measured on a single participant for knee joint angles of 111° to 169° (approximately full extension) using a Contrex MJ dynamometer. Maximal vol...

A multiple linear model was developed for individual tree crown width of Cunninghamia lanceolata (Lamb.) Hook in Fujian province, southeast China. Data were obtained from 55 sample plots of pure China-fir plantation stands. An Ordinary Linear Least Squares (OLS) regression was used to establish the crown width model. To adjust for correlations between observations from the same sample plots, we...

The present study aimed at analyzing and comparing longitudinally the EMG (electromyographic activity) of the superior orbicularis oris muscle according to the breathing mode. The sample, 38 adolescents with Angle Class II Division 1 malocclusion with predominantly nose (PNB) or mouth (PMB) breathing, was evaluated at two different periods, with a two-year interval between them. For that purpos...

Weak electric fields modulate neuronal activity, and knowledge of the interaction threshold is important in the understanding of neuronal synchronization, in neural prosthetic design, and in the public health assessment of environmental extremely low frequency fields. Previous experimental measurements have placed the threshold between 1 and 5 mV/mm, although theory predicts that elongated neur...