Addition of 1-3 mM-8-bromo-cyclic AMP to monolayer cultures of H-4 rat hepatoma cells resulted in a rapid but short-lived increase in tyrosine aminotransferase (EC 2.6.1.5) activity. The transient nature of this induction is due to desensitization to 8-bromo-cyclic AMP. Throughout this time course of induction and desensitization, removal of 8-bromo-cyclic AMP resulted in a rapid and significan...

background: preterm premature rupture of membranes (pprom) occurs in 3% of pregnancies and 30-40% of preterm labors are related to this problem. early diagnosis of pprom is very important due to its impact on pregnancy outcomes. objective: to determine the diagnostic value of aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels in vaginal fluid for the diagnosis of preterm...

Denervated dog gastrocnemius muscle has shown a progressive decrease in total protein content, alanine aminotransferase (AIAT), aspartate aminotransferase (AAT) and glutamate dehydrogenase (GDH) activity levels and elevation in free amino acid, ammonia, urea, glutamine contents and AMP deaminase activity levels during post-neurectemic days. The possible implications of these findings are discus...

Incubation of rat hepatocytes with epinephrine inhibited alanine aminotransferase (ALT) (80%) and aspartate aminotransferase (AST) (53%) activities with no effect on lactate dehydrogenase (LDH) activity. Injection of epinephrine caused a progressive increase with time in hepatic LDH activity, being 52% at 24 h. Preinjection with propranolol eliminated the hormone effect and caused further ...

Kynureninase activity in fetal tissue of rat is two thirds the level of the adult, while kynurenine aminotransferase (L-kynurenine: 2-oxoglutarate aminotransferase, EC. 2. 6. 1. 7) activity could not be observed at all in fetal tissue. The latter began to arise after birth and reached the adult level at 50 g of body weight. This fact suggests that anthranilic acid in fetal tissue might have som...

freshwater fish cirrhinus mrigala were exposed to lethal concentration (5 mg/l) for 1,2,3,4 days and sublethal concentration (1 mg/l) for 1,7,14,21 days of cypermethrin to examine the enzymes activity, in functionally three different tissues namely, gill, liver and muscle. activities of aspartate aminotransferase (aat), alanine aminotransferase (alat) and glutamate dehydrogenase (gdh) increased...